含衍生自细胞巨大病毒的免疫原组成物及其使用方法 【技术领域】
本发明涉及一种抗疱疹病毒(herpesvirus)的疫苗，尤其涉及产生抗疱疹病毒的免疫作用细胞(immune effector cells)的免疫原组成物。本发明还涉及有关于前述的免疫原组成物的用途以及其应用于活化免疫细胞的方法，属于疫苗领域。
背景技术
疱疹病毒属于疱疹病毒科(Herpes viridae)病毒，目前已知有八种病毒可造成人类疾病，这类病毒被统称为人类疱疹病毒(human herpesvirus，HHV)，其中包括(1)人类疱疹病毒-1(human herpesvirus-1，HHV-1)，亦是单纯疱疹病毒-1(herpessimplexvirus-1，HSV-7)；(2)人类疱疹病毒-2(HHV-2)，亦是单纯疱疹病毒-2(HSV-2)；(3)人类疱疹病毒-3(HHV-3)，即带状疱疹病毒(VaricellaZosterVirus，VZV)，会引起水痘和带状疱疹，又称水痘病毒；(4)人类疱疹病毒-4(HHV-4)，即艾普斯坦-巴尔二氏病毒(Epstein-BarrVirus，EBV)，是一种淋巴细胞病毒，会引起伯奇氏淋巴瘤和鼻咽癌；(5)人类疱疹病毒-5(HHV-5)，即细胞巨大病毒(cytomegalovirus，CMV)；(6)人类疱疹病毒-6(HHV-6)，即玫瑰疹病毒，会造成第六症，包括婴儿玫瑰疹和幼儿急疹；(7)人类疱疹病毒-7(HHV-7)，与HHV-6相近，引起的症状也大致相同；以及(8)人类疱疹病毒-8(HHV-8)，其是猴病毒属，简称作kSHV，可在卡波西氏肉瘤中发现。
现有技术对于移植受者的疱疹病毒(herpesvirus，HV)的感染管理主要是使用抗病毒试剂进行先行性治疗(preemptive treatment)或预防治疗(prophylaxis)。以细胞巨大病毒(cytomegalovirus，CMV)为例，前者为当培养试验呈阳性或检验显示病毒正主动复制，虽无症状即先行治疗，后者则针对血清阳性者虽无感染证据即行预防治疗。现有技术所使用的数种用以控制CMV复制的抗病毒试剂包括更昔洛韦(ganciclovir)、膦甲酸(foscarnet)以及西多福韦(cidofovir)(GandhiMK，etal.，LancetInfect.Dis.，2004，4：725-38)。对于移植受者通过该等试剂作为治疗以控制疱疹病毒感染目前已有显着的进步。
然而，这些药理学策略(pharmacological strategies)具有其限制，诸如药物毒性、抗药性的发生、不佳的口服生物可利用性(oral bioavailability)以及低效力等问题。死亡率在即使已利用抗病毒试剂治疗的情况下仍然偏高，特别是于疗程中未尽早开始治疗(GandhiMK，etal.，同上述；IsonMG，etal.，Clin.ChestMed.，2005，26：691-705；GandhiMK，etal.，BloodRev.，2003，17：259-64)。此外，当病患长期使用这些试剂，对于抗病毒试剂的抗药性会逐渐产生(IsonMG，etal.，同上述；BironKK.，AntiviralRes.，2006，71：154-63)。
现有针对疱疹病毒感染疾病的免疫疗法是使用以活病毒为基础的疱疹病毒抗原来源(herpesvirus antigen sources based on live virus)、经疱疹病毒感染的细胞(herpesvirus-infected cells)、疱疹病毒基因表达载体(herpesvirus gene expressionvector)或者合成的疱疹病毒蛋白或多肽，通过刺激用于活化疱疹病毒-专一的免疫反应的抗原呈现细胞(antigen presenting cells)。使用病毒或经病毒感染的细胞作为抗原来源存在有病毒污染以及导致感染的潜在风险；而使用全长疱疹病毒基因或蛋白质作为抗原来源则又有诱发免疫抑制作用(immune suppression)或免疫耐受性(immune tolerance)的潜在风险。
【发明内容】
基于现有技术具有前述包括因病毒污染而感染以及免疫耐受性等问题，本发明目的在于提供一种针对疱疹病毒疾病的免疫疗法，其不会有如前述使用活病毒、经疱疹病毒感染细胞或全长疱疹病毒蛋白质所产生的种种问题。
为达到上述目的，在第一方面，本发明提供一种含衍生自细胞巨大病毒(cytomegalovirus，CMV)的多肽的免疫原组成物(immunogenic composition)，其包含：(a)CMV pp65以及CMV IE-1多肽所衍生的多肽片段的至少其中之一；以及(b)选自于由下列所构成的群组的多肽：由CMV VGLB、CMV VPAP以及CMVp100多肽所衍生的多肽片段以及它们的组合。
在第二方面，本发明一种含衍生自细胞巨大病毒的多肽的免疫原组成物(immunogenic composition)，其包含(a)CMV pp65以及CMV IE-1多肽所衍生的多肽库中的至少其中之一；以及(b)选自于由下列所构成的群组的多肽库：由CMV VGLB、CMV VPAP以及CMV p100多肽所衍生的多肽库以及它们的组合。
在第三方面，本发明提供一种含衍生自细胞巨大病毒的多肽的免疫原组成物，其包含CMV VGLB多肽所衍生的多肽片段。
在第四方面，本发明提供一种含衍生自细胞巨大病毒的多肽的免疫原组成物，其包含CMV VGLB多肽所衍生的多肽库。
在本发明一较佳的实施例中，所述的免疫原组成物，其中该CMV pp65具有与SEQ ID NO：1实质上相同的序列；该CMV IE-1具有与SEQ ID NO：2实质上相同的序列；该CMV VGLB具有与SEQ ID NO：3实质上相同的序列；该CMVVPAP具有与SEQ ID NO：4实质上相同的序列；以及该CMV p100具有与SEQ IDNO：5实质上相同的序列。
较佳的是，所述的免疫原组成物，其包含CMV pp65、CMV IE-1、CMVVGLB、CMV VPAP以及CMV p100多肽所衍生的多肽库。
在第五方面，本发明提供如前述第一至第四方面的任一免疫原组成物于活体外诱发针对疱疹病毒的免疫反应上的用途。
在第六方面，本发明提供如前述第一至第四方面的任一免疫原组成物用于制造治疗疱疹病毒感染疾病地医药品上的用途。
在第五方面，本发明提供一种于活体外(ex vivo)生产可活化免疫细胞的树状细胞的方法，其包含下列步骤：将一树状细胞以及一前述第一至第四方面的任一免疫原组成物予以混合成一树状细胞混合培养物；以及令该树状细胞混合培养物于一适当培养基中进行一培养，以获取一可活化免疫细胞的树状细胞。
在第六方面，本发明提供一种于活体外(ex vivo)诱发产生免疫作用细胞(immune effector cells)的方法，其包含下列步骤：提供一种如前述第一至第四方面之任一方法所制得的可活化免疫细胞的树状细胞以及一种免疫细胞(immunecells)；以及将该可活化免疫细胞的树状细胞以及免疫细胞共培养于一适当的培养基中，以获取一免疫作用细胞。
本发明免疫原组成物被证实可以有效的活化抗-CMV免疫反应(anti-CMVimmune response)，且由于该等多肽库没有使用活病毒、经CMV感染细胞，亦非全长CMV蛋白质，因此不会产生感染问题以及免疫抑制作用、免疫耐受性等潜在风险。此外，依据本发明方法可有效活化树状细胞，并用以进一步活化免疫细胞，并产生具有抗CMV病毒活性的免疫作用细胞。
发明的详细说明
在本发明中，申请人研发出一种用于产生抗疱疹病毒的免疫作用细胞(immune effector cells)的免疫原组成物以及方法。该CMV免疫原组成物包括复数由全长CMV蛋白质衍生的多肽(peptide)。申请人发现2、3、4或5种CMV多肽库组成的混合库(mixed pool)相较于单一的或双重的CMV蛋白质衍生的多肽可以更为有效的活化抗-CMV免疫反应(anti-CMV immune response)，其中CMV专一性的CD8+以及CD4+T细胞被证实可以被活化而产生高的作用功能(effector functions)。显示本发明CMV免疫原组成物以及免疫治疗方法可以被使用来预防以及治疗疱疹病毒相关疾病。
因此，本发明于一方面系提供一种含衍生自细胞巨大病毒(CMV)的多肽的免疫原组成物(immunogenic composition)，其包含：(a)CMV pp65以及CMV IE-1多肽所衍生的多肽片段的至少其中之一；以及(b)选自于由下列所构成的群组的多肽：由CMV VGLB、CMV VPAP以及CMV p100多肽所衍生的多肽片段以及它们的组合。
本发明于另一方面提供一种含衍生自细胞巨大病毒的多肽的免疫原组成物(immunogenic composition)，其包含(a)CMV pp65以及CMV IE-1多肽所衍生的多肽库中的至少一者；以及(b)选自于由下列所构成的群组的多肽库：由CMVVGLB、CMV VPAP以及CMV p100多肽所衍生的多肽库以及它们的组合。
本发明于另一方面亦提供一种含衍生自细胞巨大病毒的多肽的免疫原组成物，其包含CMV VGLB多肽所衍生的多肽片段。
本发明于另一方面亦提供一种含衍生自细胞巨大病毒的多肽的免疫原组成物，其包含CMV VGLB多肽所衍生的多肽库。
CMV pp65为一种CMV结构蛋白质(structural protein)，其是指HCMV的磷酸化基质蛋白(phosphorylated matrix protein)，其具有下列特性：(1)名称：pp65，65kDa较小的基质磷酸蛋白(lower matrix phosphoprotein)，亦即外壳蛋白UL83(Tegument protein UL83)；(2)所属有机体种类(Organism)：人类细胞巨大病毒(Human cytomegalovirus)，属于人类疱疹病毒-5(Human herpesvirus-5，HHV-5)；(3)序列长度：561胺基酸；以及(4)功能：形成HCMV病毒粒子(virion)基质的一部分。较佳的具体实例为具有编号为Swiss-Prot：P06725的序列、NCBI AccessionNO：NP 040018或如SEQ ID NO：1的序列。
CMV IE-1为一种CMV的主要立即早期蛋白质-1(major immediate earlyprotein-1)，其为一种转录调节蛋白质(transcription regulatory protein)，其具有下列特性：(1)名称：IE-1，亦即UL123；(2)所属有机体种类：人类细胞巨大病毒，属于HHV-5；(3)序列长度：491胺基酸；以及(4)功能：属于立即早期转录调节子，可增强EI-2对于E1.7启动子(promoter)的活化。较佳的具体实例为具有编号为Swiss-Prot：P13202的序列、NCBI Accession NO：NP 040060或如SEQ IDNO：2的序列。
CMV VGLB为一种CMV的病毒外套醣蛋白(viral envelope glycoprotein)，其具有下列特性：(1)名称：醣蛋白B，又明醣蛋白GP55，亦即UL55；(2)所属有机体种类：人类细胞巨大病毒，属于HHV-5；(3)序列长度：907氨基酸；以及(4)功能：属于第一型膜蛋白(Typel membrane protein)，其为CD209/DC-SIGN病毒配位子，其等之间的作用可使得病毒颗粒为树状细胞所捕捉，并将其转移给容陈细胞(permissive cells)。较佳的具体实例为具有编号为NCBI AccessionNO：YP 081514的序列，或如SEQ ID NO：3的序列。
CMV VPAP为一种CMV的聚合酶连续性因子(DNA polymerase processivityfactor)，即HCMV聚合酶蛋白质的次单元，其具有下列特性(1)名称：DNA聚合酶连续性因子，又名聚合酶辅助蛋白质(Polymerase accessory protein，PAP)，亦即UL44；(2)所属有机体种类：人类细胞巨大病毒，属于HHV-5；(3)序列长度：433胺基酸；以及(4)功能：DNA聚合酶的辅助性次单元(accessory subunit)，其作用在于增加聚合反应的连续性。较佳的具体实例为具有编号为NCBI AccessionNO：AAO73452的序列，或如SEQ ID NO：4的序列。
CMV p100为一种CMV的外壳蛋白，其是指一大小为150KDa的HCMV基质磷酸蛋白(phosphoprotein)，其具有下列特性(1)名称：PP150，又名碱性磷酸蛋白(Basic phosphoprotein，BPP)，亦即UL32；(2)所属有机体种类：人类细胞巨大病毒，属于HHV-5；(3)序列长度：1046胺基酸；以及(4)功能：CMV大的结构磷酸蛋白质。较佳的具体实例为具有编号为NCBI ACCESSION NO：AAG31644的序列，或如SEQ ID NO：5的序列。
在本发明较佳的实施例中，所述的CMV pp65、IE-1、VGLB、VPAP以及CMV p100多肽系分别具有与前述对应序列实质上相同的序列。
依据本发明，用语「所衍 生的多肽片段」是指具有所述蛋白质序列的全部或一部分序列的多肽或多肽片段。
依据本发明，用语「实质上相同」意指在不同物种之中，由于胺基酸序列的变异并不必然影响其所构成蛋白质的活性，因此只要氨基酸序列具有一定程度的相似度而不影响该蛋白质的活性。上述一定程度的相似度较佳的是70％以上；更佳的是80％以上；以及又更佳的是90％以上。
在本发明较佳的实施例中，前述的免疫原组成物包含CMV pp65、CMVIE-1、CMV VGLB、CMV VPAP以及CMV p100多肽所衍生的多肽库。如此处所使用的用语「多肽库(peptide pool)」是指一种扩延(spanning)一基因产物整体序列的具有部分氨基酸重迭的多肽所构成。
在本发明较佳的实施例中，其中各多肽所衍生的多肽库中各多肽具有一大小介于12至18个氨基酸之间。
在本发明较佳的实施例中，其中各个多肽库中二相邻的多肽的序列具有介于10至15个连续氨基酸残基之间的重迭。
举例而言，其中若前述多肽所衍生的多肽库是一「十五多肽库(pentadecapeptides)」，其意指一种扩延(spanning)一基因产物整体序列的具有部分氨基酸重迭(overlapping)的15员多肽所构成的多肽库(peptide pool)，同理，具有其他大小的多肽的多肽库也同样如此。
在本发明的较佳的具体例中，各多肽所衍生的十五多肽库中二相邻的十五多肽具有11个连续氨基酸残基重迭。例如，CMV的pp65基因的基因产物(SEQID NO：1)具有561氨基酸，其中一种15员多肽是具有第1至15位置的连续15个氨基酸序列，而其相邻的15员多肽是为一具有第5至15位置的连续的11个氨基酸部分重迭以及以及接续的第16至19位置的4个连续的氨基酸残基序列，并依此类推，余不足4个连续的氨基酸残基时，通过增加重迭部分的氨基酸序列，以满足各多肽为15员(15-mer)的条件。
依据本发明，所述的多肽库可以通过技术领域中所熟知的方法合成。在本发明的较佳的具体例中，所述的多肽库是由人工合成的多肽所构成。
依据本发明，所述的多肽库中的相邻的多肽意指具有设定的最大重迭的连续的氨基酸序列的二多肽，以前述15员肽之多肽库为例，若该多肽库设定为具有11个连续的胺基酸序列重迭，则该相邻的二多肽分别于靠近C端之11个连续胺基酸序列及靠近N端之11个连续胺基酸序列系为相同的。
本发明于另一方面系提供一种的免疫原组成物，其包含一CMV pp65多肽所衍生的多肽库以及一CMV IE-1多肽所衍生的多肽库之至少一者，其中该CMV pp65多肽所衍生的多肽库包括具有如SEQ ID NO：6至143所述序列之多肽；而该CMV IE-1多肽所衍生的多肽库包括具有如SEQ ID NO：144至263所述序列的多肽。
在本发明较佳的实施例中，前述的免疫原组成物进一步包含选自于下列者所构成之群组的多肽库：含有具有如SEQ ID NO：264至487所述序列的多肽的多肽库；含有具有如SEQ ID NO：488至593所述序列的多肽的多肽库；含有具有如SEQ ID NO：594至852所述序列的多肽多的多肽库以及其它等多肽库的组合。
依据本发明，所述的免疫原组成物进一步包含一生理上可接受的载剂或赋型剂。
依据本发明，所述的免疫原组成物进一步包含一免疫促进剂(immuno stimulant)。
如此处所使用的用语「该免疫促进剂(immuno-stimulant)」意指任何实质上可以增进或增强一对于外来抗原的包括抗体或细胞调节的免疫反应的物质。一种较佳的免疫促进剂包含一佐剂(adjuvant)。佐剂包括被设计用来保护抗原免于快速代谢的物质，诸如氢氧化铝(aluminum hydroxide)或矿物油(mineraloil)以及一免疫反应刺激物(stimulator ofimmune responses)，诸如属于介面活性剂(surfaceactive agent)的共聚合物(copolymer)，包括脂质A(lipidA)等，另外还包括由百日咳杆菌所衍生的蛋白质(Bordetalla pertussis derived proteins)以及由所衍生的蛋白质结核分枝杆菌(Mycobacterium tuberculosis)、可以当做免疫调节剂的醣脂质，例如α-galatosylceramide(α-GalCer)及其衍生物，以及由CpG所衍生的聚核苷酸(polynucleotides)
特定的佐剂可为商业上可获得的试剂，例如：弗氏不完全佐剂及弗氏完全佐剂(Freund′s Incomplete Adjuvant and Complete Adjuvant)(Difco Laboratories，Detroit，Mich.)；Merck Adjuvant 65(Merck and Company，Inc.，Rahway，N.J.)；AS-2(Smith Kline Beecham，Philadelphia，Pa.)；铝盐(aluminum salts)，诸如氢氧化铝凝胶(aluminum hydroxide gel)或磷酸铝(aluminum phosphate)；钙、铁或锌之盐类；醯基化酪胺酸的不可溶性悬浮物(insoluble suspension of acylated tyrosine)；醯基化糖类(acylated sugars)、阳离子性或阴离子性衍生的多醣体(cationically oranionically derivatized polysaccharides)；聚磷氮烯(polyphosphazenes)；生物可分解微球体(biodegradable microspheres)；单一磷酸类脂质A(monophosphoryl lipidA)以及智利皂荚树A(Quillajasaponaria A，Quil A)；以及其他诸如GM-CSF、介白素2、-7、-12等的细胞激素(cytokine)以及其他相似的生长激素亦可作为佐剂使用。
本发明于另一方面系提供一种于活体外(ex vivo)生产可活化免疫细胞的树状细胞的方法，其包含将一树状细胞以及一如前所述的免疫原组成物予以混合成一树状细胞混合培养物；以及令该树状细胞混合培养物于一适当的培养基中进行一培养，以获取一可活化免疫细胞的树状细胞。依据本发明，所述的树状细胞(dendritic cells)是衍生自周边血液单核细胞、骨髓细胞(bone marrow cell)、造血前趋细胞(hematopoietic progenitor cell)或干细胞(stem cell)。
如此技术领域具有通常知识者所知的，树状细胞(dendritic cell)为存在于哺乳动物的一种白血球(leukocyte)，主要出现于血液、暴露于环境中的组织以及其他组织中，例如，皮肤、鼻腔、肺、胃和小肠的上皮组织等。它们的作用是调节因环境刺激所产生的先天和后天免疫反应。它的其中一个最重要的功能就是将抗原处理(process)后呈现(present)给免疫系统的其他白血球，故是一种抗原呈现细胞(antigen presenting cell)(Science，288：522-527，2000；Curr.Med.Chem.，13(14)：1591-607，2006；Nat.Rev.Cancer，8(5)：351-60，2008)。在本发明较佳的实施例中，该树状细胞是人类的树状细胞。
依据本发明，所述的适当的培养基含有细胞激素或生长激素，该细胞激素是选自于由下列所构成的群组：IL-2、IL-7、IL-15及其组合。本发明于再一方面是提供一种于活体外(ex vivo)诱发产生免疫作用细胞(immune effector cells)的方法，其包含下列步骤：提供一种如前所述的方法所制得的可活化免疫细胞的树状细胞以及一种免疫细胞(immune cells)；以及将该可活化免疫细胞的树状细胞以及免疫细胞共培养于一适当的培养基中，以获取一免疫作用细胞。
较佳的该免疫细胞是一种自体衍生的或异体的免疫细胞(autologous orallogeneic immune cells)。更佳的该免疫细胞为一种自体衍生的免疫细胞(autologous immune cells)。
如此处所使用的用语「自体衍生的(autologous)」对于所属技术领域中具有通常知识者所知者，是指源自于同一个体。举例而言，所指的自体衍生的免疫细胞(autologous immune cells)是指与所提供的树状细胞源自于自身个体的(selfsame individual)的免疫细胞，藉、以避免诱导发生非所欲的免疫反应，诸如异源性免疫反应(heterologous immune response)。
依据本发明，该免疫细胞是非贴附性的周边血液单核细胞。在本发明的一较佳的具体例中，该免疫细胞是T淋巴细胞；更佳的是，自体衍生的免疫细胞是T淋巴细胞。
基于本发明的免疫原组成物是衍生自一种属于疱疹病毒家族的细胞巨大病毒，依据本发明方法所获取的可活化免疫细胞的树状细胞也可以活化具有疱疹病毒专一性的免疫细胞，进而应用于诱发针对疱疹病毒(herpesvirus)的免疫反应。
所指的疱疹病毒可以是，但不限于：细胞巨大病毒(cytomegalovirus)、单纯疱疹病毒-1(Herpessimplexvirus-1，HSV-1)、单纯疱疹病毒-2(Herpessimplexvirus-2，HSV-2)、带状疱疹病毒(VarieellaZostervirus，VSV)、艾普斯坦-巴尔二氏病毒(Epstein-BarrVirus，EBV)、人类疱疹病毒-6(Human herpesvirus-6，HHV-6)、人类疱疹病毒-7(Human herpesvirus-7，HHV-7)以及人类疱疹病毒-8(Human herpesvirus-8，HHV-8)。
【附图说明】
图1显示经树状细胞活化的免疫细胞的制备流程。
图2显示不同CMV蛋白质所衍生多肽库及其组合刺激PBMC的细胞产生增殖作用的效果，其中A区为CFSE染色分析结果，而B区为细胞内细胞激素染色分析的结果。
图3显示不同CMV蛋白质所衍生多肽库及其组合刺激PBMC的细胞产生免疫反应的效果，其中A区、B区分别来自于不同捐赠者的PBMC的试验结果。
图4显示不同CMV蛋白质所衍生多肽库及其组合对于PBMC中的CD4+以及CD8+族群的细胞的增殖作用的影响。
图5A区以及B区显示以不同的CMV蛋白质所衍生多肽库及其组合刺激不同来源的PBMC，在PBMC的细胞激素分泌情形。
图6显示以具有五种CMV蛋白质所衍生的十五多肽库的混合库予以处理的树状细胞(DCs pulsed with the mixed pool of 5CMV pentadecapeptides)刺激非贴附性周边血液单核细胞(non-adherent PBMC)，其中CMV-专一性作用细胞(IE)的细胞内细胞激素染色的结果。
图7为图6的结果以柱状图表示，图7A区显示各组别的IL-2的表现情形，而图7B区显示各组别的CD107a的表现情形。
【具体实施方式】
本发明将进一步通过下面的实施例来作说明，但应明了的是，该等实施例仅为说明之用，而不应被视为本发明的实施上的限制。
实施例
实验材料与方法
1.多肽以及抗原
使用于下面实施例中的15员多肽库(15-mer peptide pools)是购自于JPT Peptide Technologies GmbH(Berlin，Germany)，其包括扩延(spanning)以下列者整体之具有11个胺基酸部分重迭的序列的十五多肽库(pentadecapeptides)：HCMVA pp65(SEQ ID NO：1)(561个氨基酸，其所衍生的多肽库含138种多肽)、HCMVA IE-1(SEQ ID NO：2)(491个氨基酸，其所衍生的多肽库含120种多肽)、HCMVA VPAP(SEQ ID NO：3)(433个氨基酸，所衍生的多肽库含106种多肽)、HCMVA p100(SEQ ID NO：4)(1048个氨基酸，所衍生的多肽库含259种多肽)以及HCMVT VGLB(SEQ ID NO：5)(907个氨基酸，所衍生的多肽库含224种多肽)。其他抗原及多肽可以通过不同方法合成。其中由WT-1(Wilm’stumorl)(Swissprot：P19544；其序列如SEQ ID.NO：854所示)所衍生的多肽库(WT33；JPT Peptide Technologies GmbH，Berlin，Germany)以及由C型肝炎病毒的核心病毒(core protein of Hepatitis C virus)(NCBIACCESSION：ABV46234(1-191//product＝″coreprotein″；其序列如SEQ ID.NO：854所示)所衍生的多肽库，并以Peptide Scan15/1l的方式，自JPT PeptideTechnologies公司(JPT Peptide Technologies GmbH，B erlin，Germany订购，其等系被用来作为非专一性多肽库。
2.周边血液单核细胞(peripheral blood mononuclear cells，PBMCs)的分离
血浆析离的血液(apheresis blood)以及全血取自于健康的捐赠者。周边血液单核细胞如先前所述的使用Ficoll-Hypaque(GE HealthcareBio-SciencesAB，NJ，USA)通过梯度密度离心予以制备(HanS.etal.，2008，MolecularTherapy，16：269-279)。人类周边血液单核细胞的存活率通过锥虫蓝染色(trypanblue staining)予以测定，只有细胞存活率大于80％的组别的细胞被使用于下面的
实施例中。
3.树状细胞(dendritic cells，DC)的制备
将周边血液单核细胞以1x107细胞/孔(cells/well)的细胞密度置于6孔盘中，以将周边血液单核细胞培养于AIM-V培养基(Gibco-BRL，CA，USA)中历时2小时进行贴附。接而，温和的移除未贴附的细胞(non-adherent cells)，并且进行冷冻作为用于后续共培养实验中的T淋巴细胞(T lymphocytes)的来源。将贴附的细胞(adherent cells)予以培养于添加有50ng/mL的GM-CSF(Biosource，CA，USA)以及25ng/mL的IL-4(Biosource，CA，USA)的AIM-V培养基中。为了产生树状细胞，细胞以GM-CSF以及IL-4培养历时24小时，再以IFN-γ(20ng/mL)(Gentaur)、TNF-α(50ng/mL)(R&Dsystems，MN，USA)、IL-1β(10ng/mL)(R&Dsystems，MN，USA)、IL-6(10ng/ml)(R&Dsystems)以及PGE2(1μM)(Sigma-Aldrich，MO，USA)培育24小时，作为成熟化反应(maturation)。树状细胞的表现型(phenotype)通过流式细胞分析法分析。
4.以树状细胞活化且经体外(ex vivo)扩增的抗原专一性免疫细胞
请配合第一图所示，所述方法大致是以图中所示的流程来进行。经树状细胞活化的免疫细胞是依据先前所述的方法制备(Hanetal.，同上述)。简言之，成熟的树状细胞被装载(loaded)以多肽(5μg/mL)或其他抗原历时3小时并予以辐射照射(2，500rads)。树状细胞与同源性非贴附性周边血液单核细胞(PBMC)以1∶20的比例予以共培养于具有2％人类AB血清的AIM-V培养基中。于第三天，予以添加IL-2(Gentaur，Aachen，Germany)、IL-7(Gentaur)以及IL-15(Gentaur)。接着，每隔一天予以添加新鲜的具有该等细胞激素(cytokines)的培养基。共培养物中的T细胞的功能分析是透过细胞内细胞激素染色(intracellular cytokine staining)来进行。
5.以羟基萤光素二醋酸盐琥珀醯亚胺酯为基础的细胞增殖分析法(carboxyfluorescein diacetate succinimidylester-based cell proliferatinganalysis，CFSE-based cell proliferating analysis)
简言之，1x106PBMCs利用羟基萤光素二醋酸盐琥珀醯亚胺酯(CFSE)予以标记，接而利用抗原刺激培养。于第三天，予以添加IL-2(Gentaur，Aachen，Germany)以及IL-15(Gentaur)。接而，每隔一天予以添加新鲜的具有该等细胞激素(cytokines)之培养基直到第7天为止，细胞针对CD4及CD8染色，并以流式细胞分析法分析。
6.CD107a以及细胞内细胞激素染色(CD107a and intracellular cytokinestaining)
细胞染色的分析是如Han等人的著作所述者予以进行(Hanetal.，同上述)。简言之，3x105的经扩增的CMV专一性免疫作用细胞(expanded CMV immuneeffector，IE)使用经抗原装载的同源性树状细胞(anitgen-loaded autologous DCs)或单核细胞于有或没有抗-CD107a-FITC的AIM-V培养基中予以进行刺激。于刺激反应1小时后，予以添加孟宁素(Monensin)(Sigma)。于5小时后，细胞针对CD4及CD8染色、固定(fixed)、穿孔(permeablized)并且利用针对IFN-γ、TNF-α或IL-2的抗体(全部来自于BD Bioscience)并使用FIX/PERM以及PERM/Washsolution(BD)予以染色。
7.酵素连结免疫斑点分析(Enzyme-linked Immuno Spot assay，ELISpot assay)
新鲜分离的PBMC以1x105cell/well的浓度盛盘于涂布(coated)有10μg/mlanti-IFN-γ(1-D1K；MabTech)的96-孔盘并且使用5％去活性人类AB血清(inactivated human AB serum)(Valley B iomedical，USA)予以阻隔(block)。细胞利用不同的多肽库的组合以二重复的方式进行刺激反应。于37℃于5％CO2下培育18至20小时后，将细胞予以冲离并将1μg/ml经生物素标记的抗-IFN-γ(biotinlabeled anti-IFN-γ)(7-B6-1；MabTech)予以加入。通过加入链霉抗生物素标记的碱性磷酸酯酶(Streptavidin conjugated alkaline phosphatase，Streptavidin conjugatedALP)(MabTech)以产生一呈色反应(color reaction)[斑点(spots)]，继而加入将受质BCIP/NBT-plus(Bio-Rad)。斑点的数目藉由ELISPOT读取仪(ELISPOT reader)(Auto Immune Diagnostika)计算出，以每106PBMC中含有斑点形成细胞(spot-forming cell，SFC)表示。
实施例1以不同CMV蛋白质所衍生的多肽库或其组合刺激周边血液单核细胞(PBMC)的功效分析---利用CFSE染色方法
本实施例的目的在于利用不同的CMV蛋白质所衍生的多肽库及其组合刺激周边血液单核细胞，并利用CFSE染色分析不同的CMV蛋白质所衍生的多肽库及其组合对于周边血液单核细胞的细胞的增殖活性的影响，以了解不同组合对于刺激免疫反应产生的效果。
经CFSE-标记的周边血液单核细胞(PBMC)分别依据「实验材料与方法」中所述的方法，并分为如下所述组别以不同的多肽库组合刺激周边血液单核细胞，进行培养历时7天：
(1)pp65的十五多肽库(CMV pentadecapeptides)，样品「1」表示；
(2)VGLB的十五多肽库，以样品「2」表示；
(3)IE-1的十五多肽库，以样品「3」表示；
(4)p100的十五多肽库，以样品「4」表示；
(5)VPAP的十五多肽库，以样品「5」表示；
(6)pp65及VGLB的十五多肽库，以样品「6」表示；
(7)pp65及IE-1的十五多肽库，以样品「7」表示；
(8)VGLB及IE-1的十五多肽库，以样品「8」表示；
(9)pp65、VGLB及IE-1的十五多肽库，以样品「9」表示；
(10)pp65、VGLB、IE-1及p100的十五多肽库，以样品「10」表示；以及
(11)pp65、VGLB、IE-1、p100及VPAP的十五多肽库，以样品「11」表示。
此外，以下列组别作为对照组：
(12)经CFSE-标记的周边血液单核细胞单独培养作为未刺激对照组(nostimulation control)，以样品「12」表示，作为实验的背景值；
(13)经CFSE-标记的周边血液单核细胞与经C型肝炎病毒的核心病毒(coreprotein ofHepatitis C virus)所衍生的多肽库装载的树状细胞共培养，作为负对照组(Negative control)，以样品「13」表示。
上述经刺激的PBMC接而以如「实验材料与方法」中所述的方法进行抗原专一性细胞增殖(antigen-specific proliferation)与之分析，并进行「细胞内细胞激素染色」分析，并将所得实验数据皆先扣除PBMC的数值，再绘制为图表。
结果如第二图所示，第二图A区显示在不同的多肽库组合刺激下细胞增生的情形；第二图B区则显示在不同的多肽库组合下所增生的细胞，其表现IFN-γ的能力。
由上述结果可得知：(1)五种CMV蛋白质所衍生的多肽库单独使用时皆有反应；(2)有如pp65，VGLB以及p100单一多肽所衍生的多肽库也可以诱发免疫反应；(3)两种以上的多肽库组合比单一多肽库得到的结果较好；以及(4)在这五种CMV蛋白质所衍生的多肽库中，以pp65及VGLB这两种多肽库的免疫反应比较强，组合后免疫反应有加成的效果，多肽库的组合数越多加成的效果越好。
实施例2以不同CMV蛋白质所衍生的多肽库或组合对于刺激周边血液单核细胞(PBMC)的功效分析---利用ELISpot分析方法
本实施例的目的在于利用不同的CMV蛋白质所衍生的多肽库及其组合刺激周边血液单核细胞，并利用ELISpot分析不同的CMV蛋白质所衍生的多肽库及其组合对于PBMC的细胞功能的影响。
来自不同捐赠者的新鲜分离的周边血液单核细胞分别依据「实验材料与方法」中所述的方法取得，以如下列所述的组别以不同的多肽组合刺激PBMC，进行培养予以刺激历时20小时，并利用「实验材料与方法」中所述的ELISpot分析方法进行IFN-γ分析。
(1)pp65的十五多肽库(CMV pentadecapeptides)，以样品「1」表示；
(2)VGLB的十五多肽库，以样品「2」表示；
(3)IE-1的十五多肽库，以样品「3」表示；
(4)pp65及VGLB的十五多肽库，以样品「4」表示；
(5)pp65及IE-1的十五多肽库，以样品「5」表示；
(6)pp65、VGLB及IE-1的十五多肽库，以样品「6」表示；
(7)pp65、VGLB、IE-1及p100之十五多肽库，以样品「7」表示；以及
(8)pp65、VGLB、IE-1、p100及VPAP的十五多肽库，以样品「8」表示。
结果如第三图所示，pp65+VGLB[参见长柱4(bar4)]或者pp65+IE-1[参见长柱5(bar5)]对于刺激PBMC产生IFN-γ的效果较pp65[参见长柱1(bar1)]较显着。其中，pp65+VGLB(参见长柱4)的刺激效果又较pp65+IE-1(参见长柱5)为佳。而多种CMV蛋白质所衍生的多肽库的组合的组别效果(参见长柱6、7、8)较仅具有二种CMV蛋白质所衍生的多肽库的组别(参见长柱4、5)或pp65单独的组别(参见长柱1)为佳。
实施例3以CMV蛋白质所衍生的多肽库或组合刺激PBMC各族群细胞的增殖作用分析
本实施例的目的在于利用不同的CMV蛋白质所衍生的多肽库及其组合刺激PBMC，并分析不同的CMV蛋白质所衍生的多肽库及其组合对于PBMC中的CD4+以及CD8+族群的细胞的增殖作用的影响。
经CFSE-标记的PBMC分别以(1)HCMVA pp65的十五多肽库(pentadecapeptides)，以「pp65」表示；(2)具有HCMVA pp65及HCMVA IE-1二者的十五多肽库的混合库(mixed pool)，其包含HCMVA pp65多肽库以及HCMVA IE-1多肽库，以「pp65/IE-1」表示；(3)具有HCMVA pp65、HCMVA IE-1、HCMVA VPAP、HCMVA p100、HCMVT VGLB五者的十五多肽库的混合库，以「5pepmix 」表示；(4)非专一性十五多肽库，以「WT-1」表示；(5)抗-CD3抗体，作为正对照组(positive control)，以「anti-CD3」表示等，作为刺激物，进行培养历时7天，并进行如「实验材料与方法」中所述的方法进行抗原专一性细胞增殖(antigen-specific proliferation)的分析，特别是针对CD4+以及CD8+族群的细胞的增殖作用，并以经CFSE-标记的PBMC单独培养作为未刺激对照组(nostimulation control)，以「PBMC」表示。
结果如第四图所示，各组的CFSE稀释的细胞(CFSE-diluted cells)(亦即增殖细胞)的百分比如第四图所指明。相较于具有单一CMV蛋白质所衍生的十五多肽库的混合库(pp65)或具有二种CMV蛋白质所衍生的十五多肽库的混合库(pp65/IE-1)，具有五种CMV蛋白质所衍生的十五多肽库的混合库(5pepmix)无论对于PBMC当中的CD4+或CD8+族群的细胞皆可诱发最高的增殖作用，这显示含有该五种CMV蛋白质所衍生的多肽库的组合具有最强的致免疫力(immunogenicity)。
实施例4以各种CMV蛋白质所衍生多肽库或组合刺激过的周边血液单核细胞(PBMC)的功能性分析
本实施例进一步分析通过不同的CMV蛋白质所衍生多肽库及其组合以刺激来自于不同来源的PBMC中的细胞，并分析PBMC的细胞激素分泌的情形，以判定免疫功能以确定各种组合的致免疫力。
来自于二个捐赠者的PBMC分别以(1)HCMVA pp65的十五多肽库(CMVpentadecapeptides)，以「pp65」表示；(2)具有HCMVA pp65及HCMVA IE-1二者的十五多肽库的混合库(mixed pool)，其包含HCMVA pp65多肽库以及HCMVA IE-1多肽库，以「pp65/IE-1」表示；(3)具有HCMVA pp65、HCMVA IE-1、HCMVA VPAP、HCMVA p100、HCMVT VGLB五者的十五多肽库的混合库，以「5pepmix 」表示；(4)非专一性十五多肽库，以「WT-1」表示；(5)抗-CD3抗体，作为正对照组(positive control)，以「anti-CD3」表示等作为刺激物，进行培养历时7天，并进行如「实验材料与方法」中所述的方法进行细胞内细胞激素染色分析(intracellular cytokine staining，ICCS)，针对各组别细胞的IL-2以及IFN-γ的表现分析，并以PBMC单独培养作为未刺激对照组(no stimulationcontrol)，以「PBMC only」表示。
第五图A区以及B区分别显示不同来源的PBMC经前述试验所得的结果，其中各柱状图如图式中所标明的，分别代表表现IL-2和/或IFN-γ的PBMC，结果显示相较于具有单一CMV蛋白质所衍生的多肽库的混合库(pp65)或具有二种CMV蛋白质所衍生的多肽库的混合库(pp65/IE-1)而言，具有该五种CMV抗原的多肽库的混合库(5pepmix)刺激PBMC表现IL-2和/或IFN-γ对于细胞的能力最佳，这显示具有五种CMV蛋白质所衍生的多肽库的组合具有最强的致免疫力(immunogenicity)。
实施例5由树状细胞刺激PBMC产生CMV-专一性作用细胞
本实施例利用经具有五种CMV蛋白质所衍生的十五多肽库的混合库处理的树状细胞(DCs pulsed with the mixed pool of 5CMV pentadecapeptides)刺激非贴附性周边血液单核细胞(non-adherent PBMC)，以了解其对于产生CMV-专一性作用细胞的功效。
使用具有五种CMV蛋白质所衍生的十五多肽库的混合库(mixed pool)予以处理的树状细胞以及非贴附性周边血液单核细胞(non-adherent PBMC)(作为T淋巴细胞之来源)是利用如「实验材料与方法」中所述的方法制备，并进行共培养(请参考第一图所示)。于共培养15天后将被DC活化的免疫细胞(DC-activatedimmune cells)分别针对带有单一CMV蛋白质所衍生的多肽库(pp65、IE-1、VGLB、VPAP、p100)或该五种多肽库的组合的树突细胞予以再刺激(re-stimulation)5小时，同时以佛波醇酯加上离子霉素(PMA+Ionomycin)刺激DC活化的免疫细胞(DC-activated immune cells)作为正向组别和以非专一性抗原(WT-1)处理之同源的树状细胞作为对照组。经再刺激的免疫细胞藉由对于IFN-γ、IL-2以及TNF-α的细胞内细胞激素染色(ICCS)以及对于去颗粒作用的细胞标记CD107a的染色对抗原专一性作用细胞的的功能进行评估。
第六图为前述细胞内细胞激素染色的结果，IFN-γ、IL-2以及TNF-α等细胞激素以及CD107a的表现如第六图所标示；而第七图A区以及B区系依据第六图之结果予以绘制而成的柱状图，其分别表示表现有IL-2和/或TNF-α的细胞占整体的百分比以及表现有IFN-γ和/或CD107a的细胞占整体的百分比。结果显示经由五种多肽库的组合(即CMV 5pepmix)刺激所产生的免疫细胞对于任一个单一的CMV蛋白质所衍生的十五多肽库皆有专一性反应(specific response)发生，在其中以pp65及VGLB的免疫反应最强。而五种多肽库的组合所处理过的树状细胞再刺激的组别能够于免疫作用细胞中引起最高的细胞激素产生。
前述实施例的结果显示混合有针对复数CMV蛋白质所衍生(最高至五种)的十五多肽库(pentadecapeptides)的组合在一短暂的暴露期间内可以将CD4+以及CD8+的T细胞二者同时有效地活化。CD4+以及CD8+的T细胞的抗原专一性增殖反应以及作用细胞激素(effector cytokine)的产生皆可被显着的提高，这显示CMV蛋白质所衍生的十五多肽库的组合可以作为用以建立抗-CMV免疫力的一种有效的疫苗或免疫疗法。如同于第四图及第五图所显示的，五种CMV蛋白质所衍生的十五多肽库之组合可以诱发PBMC中CD4+以及CD8+的细胞的增殖反应以及细胞激素合成。虽然单一的以及二种混合的CMV蛋白质所衍生的十五多肽库亦可刺激免疫反应，但五种CMV蛋白质所衍生的十五多肽库的组合可以产生最强的抗原专一性免疫反应。免疫作用细胞的功能藉由针对数种免疫活化细胞激素以及去颗粒作用标记CD107a的多色流式细胞分析进行分析评估。如第六及七图所示，与单一或二种CMV蛋白质所衍生的十五多肽库相比较，混合五种CMV蛋白质所衍生的十五多肽库的组合(CMV 5pepmix)在诱发作用细胞激素(effector cytokine)的产生以及CD107a的去颗粒化作用(degranulation)上是最为有效的，这进一步证实混合有五种CMV多肽库的组合是一种最为有效的CMV疫苗或免疫源(immunogen)。
以上所述，仅是本发明的较佳实施例，并非对本发明作任何形式上的限制，任何所属技术领域中具有通常知识者，若在不脱离本发明所提技术特征的范围内，利用本发明所揭示技术内容所作出局部更动或修饰的等效实施例，并且未脱离本发明的技术特征内容，均仍属于本发明技术特征的范围内。
KLPI080947_4.txt
【序列表】
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黄玉儒
杨馥鸿
<120>含衍生自细胞巨大病毒的免疫原组成物及其使用方法
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35 40 45
Arg Thr Val Leu Phe Asn Glu Leu Met Leu Trp Leu Gly Tyr Tyr Arg
50 55 60
Glu Leu Arg Phe His Asn Pro Asp Leu Ser Ser Val Leu Glu Glu Phe
65 70 75 80
Glu Val Arg Cys Ala Ala Val Ala Arg Arg Gly Tyr Thr Tyr Pro Phe
85 90 95
Gly Asp Arg Gly Lys Ala Arg Asp His Leu Ala Val Leu Asp Arg Thr
100 105 110
Glu Phe Asp Thr Asp Val Arg His Asp Ala Glu Ile Val Glu Arg Ala
115 120 125
Leu Val Ser Ala Val Ile Leu Ala Lys Met Ser Val Arg Glu Thr Leu
130 135 140
Val Thr Ala Ile Gly Gln Thr Glu Pro Ile Ala Phe Val His Leu Lys
145 150 155 160
Asp Thr Glu Val Gln Arg Ile Glu Glu Asn Leu Glu Gly Val Arg Arg
165 170 175
Asn Met Phe Cys Val Lys Pro Leu Asp Leu Asn Leu Asp Arg His Ala
180 185 190
Asn Thr Ala Leu Val Asn Ala Val Asn Lys Leu Val Tyr Thr Gly Arg
195 200 205
Leu Ile Met Asn Val Arg Arg Ser Trp Glu Glu Leu Glu Arg Lys Cys
210 215 220
Leu Ala Arg Ile Gln Glu Arg Cys Lys Leu Leu Val Lys Glu Leu Arg
225 230 235 240
Met Cys Leu Ser Phe Asp Ser Asn Tyr Cys Arg Asn Ile Leu Lys His
245 250 255
Ala Val Glu Asn Gly Asp Ser Ala Asp Thr Leu Leu Glu Leu Leu Ile
260 265 270
Glu Asp Phe Asp Ile Tyr Val Asp Ser Phe Pro Gln Ser Ala His Thr
275 280 285
Phe Leu Gly Ala Arg Pro Pro Ser Leu Glu Phe Asp Asp Asp Ala Asn
290 295 300
Leu Leu Ser Leu Gly Gly Gly Ser Ala Phe Ser Ser Val Pro Lys Lys
305 310 315 320
His Val Pro Thr Gln Pro Leu Asp Gly Trp Ser Trp Ile Ala Ser Pro
325 330 335
Trp Lys Gly His Lys Pro Phe Arg Phe Glu Ala His Gly Ser Leu Ala
340 345 350
Pro Ala Ala Asp Ala His Ala Ala Arg Ser Ala Ala Val Gly Tyr Tyr
355 360 365
Asp Glu Glu Glu Lys Arg Arg Glu Arg Gln Lys Arg Val Asp Asp Glu
370 375 380
Val Val Gln Arg Glu Lys Gln Gln Leu Lys Ala Trp Glu Glu Arg Gln
385 390 395 400
Gln Asn Leu Gln Gln Arg Gln Gln Gln Pro Pro Pro Pro Thr Arg Lys
405 410 415
Pro Gly Ala Ser Arg Arg Leu Phe Gly Ser Ser Ala Asp Glu Asp Asp
420 425 430
Asp Asp Asp Asp Asp Glu Lys Asn Ile Phe Thr Pro Ile Lys Lys Pro
435 440 445
Gly Thr Ser Gly Lys Gly Ala Ala Ser Gly Asn Gly Val Ser Ser Ile
450 455 460
Phe Ser Gly Met Leu Ser Ser Gly Ser Gln Lys Pro Thr Ser Gly Pro
465 470 475 480
Leu Asn Ile Pro Gln Gln Gln Gln Arg His Ala Ala Phe Ser Leu Val
485 490 495
Ser Pro Gln Val Thr Lys Ala Ser Pro Gly Arg Val Arg Arg Asp Ser
500 505 510
Ala Trp Asp Val Arg Pro Leu Thr Glu Thr Arg Gly Asp Leu Phe Ser
515 520 525
Gly Asp Glu Asp Ser Asp Ser Ser Asp Gly Tyr Pro Pro Asn Arg Gln
530 535 540
Asp Pro Arg Phe Thr Asp Thr Pro Val Asp Ile Thr Asp Thr Glu Thr
545 550 555 560
Ser Ala Lys Pro Pro Val Thr Thr Ala Tyr Lys Phe Glu Gln Pro Thr
565 570 575
Leu Thr Phe Gly Ala Gly Val Asn Val Pro Ala Gly Ala Gly Ala Ala
580 585 590
Ile Leu Thr Pro Thr Pro Val Asn Pro Ser Thr Ala Pro Ala Pro Ala
595 600 605
Pro Thr Pro Thr Phe Ala Gly Thr Gln Thr Pro Val Asn Gly Asn Ser
610 615 620
Pro Trp Ala Pro Thr Ala Pro Leu Pro Gly Asp Met Asn Pro Ala Asn
625 630 635 640
Trp Pro Arg Glu Arg Ala Trp Ala Leu Lys Asn Pro His Leu Ala Tyr
645 650 655
Asn Pro Phe Arg Met Pro Thr Thr Ser Thr Thr Ser Gln Asn Asn Val
660 665 670
Ser Thr Thr Pro Arg Arg Pro Ser Thr Pro Arg Ala Ala Val Thr Gln
675 680 685
Thr Ala Ser Gln Asn Ala Ala Asp Glu Val Trp Ala Leu Arg Asp Gln
690 695 700
Thr Ala Glu Ser Pro Val Glu Asp Ser Glu Glu Glu Asp Asp Asp Ser
705 710 715 720
Ser Asp Thr Gly Ser Val Val Ser Leu Gly His Thr Thr Pro Ser Ser
725 730 735
Asp Tyr Asn Asp Val Ile Ser Pro Pro Ser Gln Thr Pro Glu Gln Ser
740 745 750
Thr Pro Ser Arg Ile Arg Lys Ala Lys Leu Ser Ser Pro Met Thr Thr
755 760 765
Thr Ser Thr Ser Gln Lys Pro Val Leu Gly Lys Arg Val Ala Thr Pro
770 775 780
His Ala Ser Ala Arg Ala Gln Thr Val Thr Ser Thr Pro Val Gln Gly
785 790 795 800
Arg Val Glu Lys Gln Val Ser Gly Thr Pro Ser Thr Val Pro Ala Thr
805 810 815
Leu Leu Gln Pro Gln Pro Ala Ser Ser Lys Thr Thr Ser Ser Arg Asn
820 825 830
Val Thr Ser Gly Ala Arg Thr Ser Ser Ala Ser Ala Arg Gln Pro Ser
835 840 845
Ala Ser Ala Ser Val Leu Ser Pro Thr Glu Asp Asp Val Val Ser Pro
850 855 860
Val Thr Ser Pro Leu Ser Met Leu Ser Ser Ala Ser Pro Ser Pro Ala
865 870 875 880
Lys Ser Ala Pro Pro Ser Pro Val Lys Gly Arg Gly Ser Arg Val Gly
885 890 895
Val Pro Ser Leu Lys Pro Thr Leu Gly Gly Lys Ala Val Val Gly Arg
900 905 910
Pro Pro Ser Val Pro Val Ser Gly Ser Ala Pro Gly Arg Leu Ser Gly
915 920 925
Thr Ser Arg Ala Ala Ser Thr Thr Pro Thr Tyr Pro Ala Val Thr Thr
930 935 940
Val Tyr Pro Pro Ser Ser Thr Ala Lys Ser Ser Val Ser Asn Ala Pro
945 950 955 960
Pro Val Ala Ser Pro Ser Ile Leu Lys Pro Gly Ala Ser Ala Ala Leu
965 970 975
Gln Ser Arg Arg Ser Thr Gly Thr Ala Ala Val Gly Ser Pro Val Lys
980 985 990
Ser Thr Thr Gly Met Lys Thr Val Ala Phe Asp Leu Ser Ser Pro Gln
995 1000 1005
Lys Ser Gly Thr Gly Pro Gln Pro Gly Ser Ala Gly Met Gly Gly
1010 1015 1020
Ala Lys Thr Pro Ser Asp Ala Val Gln Asn Ile Leu Gln Lys Ile
1025 1030 1035
Glu Lys Ile Lys Asn Thr Glu Glu
1040 1045
<210>6
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>6
Met Glu Ser Arg Gly Arg Arg Cys Pro Glu Met Ile Ser Val Leu
1 5 10 15
<210>7
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>7
Gly Arg Arg Cys Pro Glu MetIle Ser Val Leu Gly Pro Ile Ser
1 5 10 15
<210>8
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>8
Pro Glu Met Ile Ser Val Leu Gly Pro Ile Ser Gly His Val Leu
1 5 10 15
<210>9
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>9
Ser Val Leu Gly Pro Ile Ser Gly His Val Leu Lys Ala Val Phe
1 5 10 15
<210>10
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>10
Pro Ile Ser Gly His Val Leu Lys Ala Val Phe Ser Arg Gly Asp
1 5 10 15
<210>11
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>11
His Val Leu Lys Ala Val Phe Ser Arg Gly Asp Thr Pro Val Leu
1 5 10 15
<210>12
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>12
Ala Val Phe Ser Arg Gly Asp Thr Pro Val Leu Pro His Glu Thr
1 5 10 15
<210>13
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>13
Arg Gly Asp Thr Pro Val Leu Pro His Glu Thr Arg Leu Leu Gln
1 5 10 15
<210>14
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>14
Pro Val Leu Pro His Glu Thr Arg Leu Leu Gln Thr Gly Ile His
1 5 10 15
<210>15
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>15
His Glu Thr Arg Leu Leu Gln Thr Gly Ile His Val Arg Val Ser
1 5 10 15
<210>16
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>16
Leu Leu Gln Thr Gly Ile His Val Arg Val Ser Gln Pro Ser Leu
1 5 10 15
<210>17
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>17
Gly Ile His Val Arg Val Ser Gln Pro Ser Leu Ile Leu Val Ser
1 5 10 15
<210>18
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>18
Arg Val Ser Gln Pro Ser LeuIle Leu Val Ser Gln Tyr Thr Pro
1 5 10 15
<210>19
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>19
Pro Ser Leu Ile Leu Val Ser Gln Tyr Thr Pro Asp Ser Thr Pro
1 5 10 15
<210>20
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>20
Leu Val Ser Gln Tyr Thr Pro Asp Ser Thr Pro Cys His Arg Gly
1 5 10 15
<210>21
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>21
Tyr Thr Pro Asp Ser Thr Pro Cys His Arg Gly Asp Asn Gln Leu
1 5 10 15
<210>22
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>22
Ser Thr Pro Cys His Arg Gly Asp Asn Gln Leu Gln Val Gln His
1 5 10 15
<210>23
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>23
His Arg Gly Asp Asn Gln Leu Gln Val Gln His Thr Tyr Phe Thr
1 5 10 15
<210>24
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>24
Asn Gln Leu Gln Val Gln His Thr Tyr Phe Thr Gly Ser Glu Val
1 5 10 15
<210>25
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>25
Val Gln His Thr Tyr Phe Thr Gly Ser Glu Val Glu Asn Val Ser
1 5 10 15
<210>26
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>26
Tyr Phe Thr Gly Ser Glu Val Glu Asn Val Ser Val Asn Val His
1 5 10 15
<210>27
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>27
Ser Glu Val Glu Asn Val Ser Val Asn Val His Asn Pro Thr Gly
1 5 10 15
<210>28
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>28
Asn Val Ser Val Asn Val His Asn Pro Thr Gly Arg Ser Ile Cys
1 5 10 15
<210>29
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>29
Asn Val His Asn Pro Thr Gly Arg Ser Ile Cys Pro Ser Gln Glu
1 5 10 15
<210>30
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>30
Pro Thr Gly Arg SerIle Cys Pro Ser Gln Glu Pro Met Ser Ile
1 5 10 15
<210>31
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>31
Ser Ile Cys Pro Ser Gln Glu Pro Met Ser Ile Tyr Val Tyr Ala
1 5 10 15
<210>32
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>32
Ser Gln Glu Pro Met Ser Ile Tyr Val Tyr Ala Leu Pro Leu Lys
1 5 10 15
<210>33
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>33
Met SerIle Tyr Val Tyr Ala Leu Pro Leu Lys Met Leu Asn Ile
1 5 10 15
<210>34
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>34
Val Tyr Ala Leu Pro Leu Lys Met Leu Asn Ile Pro Ser Ile Asn
1 5 10 15
<210>35
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>35
Pro Leu Lys Met Leu Asn Ile Pro Ser Ile Asn Val His His Tyr
1 5 10 15
<210>36
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>36
Leu Asn Ile Pro Ser Ile Asn Val His His Tyr Pro Ser Ala Ala
1 5 10 15
<210>37
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>37
Ser Ile Asn Val His His Tyr Pro Ser Ala Ala Glu Arg Lys His
1 5 10 15
<210>38
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>38
His His Tyr Pro Ser Ala Ala Glu Arg Lys His Arg His Leu Pro
1 5 10 15
<210>39
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>39
Ser Ala Ala Glu Arg Lys His Arg His Leu Pro Val Ala Asp Ala
1 5 10 15
<210>40
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>40
Arg Lys His Arg His Leu Pro Val Ala Asp Ala Val Ile His Ala
1 5 10 15
<210>41
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>41
His Leu Pro Val Ala Asp Ala Val Ile His Ala Ser Gly Lys Gln
1 5 10 15
<210>42
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>42
Ala Asp Ala Val Ile His Ala Ser Gly Lys Gln Met Trp Gln Ala
1 5 10 15
<210>43
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>43
Ile His Ala Ser Gly Lys Gln Met Trp Gln Ala Arg Leu Thr Val
1 5 10 15
<210>44
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>44
Gly Lys Gln Met Trp Gln Ala Arg Leu Thr Val Ser Gly Leu Ala
1 5 10 15
<210>45
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>45
Trp Gln Ala Arg Leu Thr Val Ser Gly Leu Ala Trp Thr Arg Gln
1 5 10 15
<210>46
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>46
Leu Thr Val Ser Gly Leu Ala Trp Thr Arg Gln Gln Asn Gln Trp
1 5 10 15
<210>47
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>47
Gly Leu Ala Trp Thr Arg Gln Gln Asn Gln Trp Lys Glu Pro Asp
1 5 10 15
<210>48
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>48
Thr Arg Gln Gln Asn Gln Trp Lys Glu Pro Asp Val Tyr Tyr Thr
1 5 10 15
<210>49
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>49
Asn Gln Trp Lys Glu Pro Asp Val Tyr Tyr Thr Ser Ala Phe Val
1 5 10 15
<210>50
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>50
Glu Pro Asp Val Tyr Tyr Thr Ser Ala Phe Val Phe Pro Thr Lys
1 5 10 15
<210>51
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>51
Tyr Tyr Thr Ser Ala Phe Val Phe Pro Thr Lys Asp Val Ala Leu
1 5 10 15
<210>52
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>52
Ala Phe Val Phe Pro Thr Lys Asp Val Ala Leu Arg His Val Val
1 5 10 15
<210>53
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>53
Pro Thr Lys Asp Val Ala Leu Arg His Val Val Cys Ala His Glu
1 5 10 15
<210>54
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>54
Val Ala Leu Arg His Val Val Cys Ala His Glu Leu Val Cys Ser
1 5 10 15
<210>55
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>55
His Val Val Cys Ala His Glu Leu Val Cys Ser Met Glu Asn Thr
1 5 10 15
<210>56
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>56
Ala His Glu Leu Val Cys Ser Met Glu Asn Thr Arg Ala Thr Lys
1 5 10 15
<210>57
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>57
Val Cys Ser Met Glu Asn Thr Arg Ala Thr Lys Met Gln Val Ile
1 5 10 15
<210>58
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>58
Glu Asn Thr Arg Ala Thr Lys Met Gln Val Ile Gly Asp Gln Tyr
1 5 10 15
<210>59
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>59
Ala Thr Lys Met Gln Val Ile Gly Asp Gln Tyr Val Lys Val Tyr
1 5 10 15
<210>60
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>60
Gln Val Ile Gly Asp Gln Tyr Val Lys Val Tyr Leu Glu Ser Phe
1 5 10 15
<210>61
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>61
Asp Gln Tyr Val Lys Val Tyr Leu Glu Ser Phe Cys Glu Asp Val
1 5 10 15
<210>62
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>62
Lys Val Tyr Leu Glu Ser Phe Cys Glu Asp Val Pro Ser Gly Lys
1 5 10 15
<210>63
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>63
Glu Ser Phe Cys Glu Asp Val Pro Ser Gly Lys Leu Phe Met His
1 5 10 15
<210>64
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>64
Glu Asp Val Pro Ser Gly Lys Leu Phe Met His Val Thr Leu Gly
1 5 10 15
<210>65
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>65
Ser Gly Lys Leu Phe Met His Val Thr Leu Gly Ser Asp Val Glu
1 5 10 15
<210>66
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>66
Phe Met His Val Thr Leu Gly Ser Asp Val Glu Glu Asp Leu Thr
1 5 10 15
<210>67
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>67
Thr Leu Gly Ser Asp Val Glu Glu Asp Leu Thr Met Thr Arg Asn
1 5 10 15
<210>68
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>68
Asp Val Glu Glu Asp Leu Thr Met Thr Arg Asn Pro Gln Pro Phe
1 5 10 15
<210>69
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>69
Asp Leu Thr Met Thr Arg Asn Pro Gln Pro Phe Met Arg Pro His
1 5 10 15
<210>70
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>70
Thr Arg Asn Pro Gln Pro Phe Met Arg Pro His Glu Arg Asn Gly
1 5 10 15
<210>71
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>71
Gln Pro Phe Met Arg Pro His Glu Arg Asn Gly Phe Thr Val Leu
1 5 10 15
<210>72
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>72
Arg Pro His Glu Arg Asn Gly Phe Thr Val Leu Cys Pro Lys Asn
1 5 10 15
<210>73
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>73
Arg Asn Gly Phe Thr Val Leu Cys Pro Lys Asn Met Ile Ile Lys
1 5 10 15
<210>74
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>74
Thr Val Leu Cys Pro Lys Asn Met Ile Ile Lys Pro Gly Lys Ile
1 5 10 15
<210>75
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>75
Pro Lys Asn Met Ile Ile Lys Pro Gly Lys Ile Ser His Ile Met
1 5 10 15
<210>76
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>76
Ile Ile Lys Pro Gly Lys Ile Ser His Ile Met Leu Asp Val Ala
1 5 10 15
<210>77
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>77
Gly Lys Ile Ser His Ile Met Leu Asp Val Ala Phe Thr Ser His
1 5 10 15
<210>78
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>78
His Ile Met Leu Asp Val Ala Phe Thr Ser His Glu His Phe Gly
1 5 10 15
<210>79
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>79
Asp Val Ala Phe Thr Ser His Glu His Phe Gly Leu Leu Cys Pro
1 5 10 15
<210>80
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>80
Thr Ser His Glu His Phe Gly Leu Leu Cys Pro Lys Ser Ile Pro
1 5 10 15
<210>81
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>81
His Phe Gly Leu Leu Cys Pro Lys Ser Ile Pro Gly Leu Ser Ile
1 5 10 15
<210>82
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>82
Leu Cys Pro Lys Ser Ile Pro Gly Leu Ser Ile Ser Gly Asn Leu
1 5 10 15
<210>83
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>83
Ser Ile Pro Gly Leu Ser Ile Ser Gly Asn Leu Leu Met Asn Gly
1 5 10 15
<210>84
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>84
Leu Ser Ile Ser Gly Asn Leu Leu Met Asn Gly Gln Gln Ile Phe
1 5 10 15
<210>85
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>85
Gly Asn Leu Leu Met Asn Gly Gln Gln Ile Phe Leu Glu Val Gln
1 5 10 15
<210>86
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>86
Met Asn Gly Gln Gln Ile Phe Leu Glu Val Gln Ala Ile Arg Glu
1 5 10 15
<210>87
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>87
Gln Ile Phe Leu Glu Val Gln Ala Ile Arg Glu Thr Val Glu Leu
1 5 10 15
<210>88
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>88
Glu Val Gln Ala Ile Arg Glu Thr Val Glu Leu Arg Gln Tyr Asp
1 5 10 15
<210>89
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>89
Ile Arg Glu Thr Val Glu Leu Arg Gln Tyr Asp Pro Val Ala Ala
1 5 10 15
<210>90
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>90
Val Glu Leu Arg Gln Tyr Asp Pro Val Ala Ala Leu Phe Phe Phe
1 5 10 15
<210>91
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>91
Gln Tyr Asp Pro Val Ala Ala Leu Phe Phe Phe Asp Ile Asp Leu
1 5 10 15
<210>92
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>92
Val Ala Ala Leu Phe Phe Phe Asp Ile Asp Leu Leu Leu Gln Arg
1 5 10 15
<210>93
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>93
Phe Phe Phe Asp Ile Asp Leu Leu Leu Gln Arg Gly Pro Gln Tyr
1 5 10 15
<210>94
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>94
Ile Asp Leu Leu Leu Gln Arg Gly Pro Gln Tyr Ser Glu His Pro
1 5 10 15
<210>95
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>95
Leu Gln Arg Gly Pro Gln Tyr Ser Glu His Pro Thr Phe Thr Ser
1 5 10 15
<210>96
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>96
Pro Gln Tyr Ser Glu His Pro Thr Phe Thr Ser Gln Tyr Arg Ile
1 5 10 15
<210>97
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>97
Glu His Pro Thr Phe Thr Ser Gln Tyr Arg Ile Gln Gly Lys Leu
1 5 10 15
<210>98
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>98
Phe Thr Ser Gln Tyr Arg Ile Gln Gly Lys Leu Glu Tyr Arg His
1 5 10 15
<210>99
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>99
Tyr Arg Ile Gln Gly Lys Leu Glu Tyr Arg His Thr Trp Asp Arg
1 5 10 15
<210>100
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>100
Gly Lys Leu Glu Tyr Arg His Thr Trp Asp Arg His Asp Glu Gly
1 5 10 15
<210>101
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>101
Tyr Arg His Thr Trp Asp Arg His Asp Glu Gly Ala Ala Gln Gly
1 5 10 15
<210>102
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>102
Trp Asp Arg His Asp Glu Gly Ala Ala Gln Gly Asp Asp Asp Val
1 5 10 15
<210>103
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>103
Asp Glu Gly Ala Ala Gln Gly Asp Asp Asp Val Trp Thr Ser Gly
1 5 10 15
<210>104
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>104
Ala Gln Gly Asp Asp Asp Val Trp Thr Ser Gly Ser Asp Ser Asp
1 5 10 15
<210>105
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>105
Asp Asp Val Trp Thr Ser Gly Ser Asp Ser Asp Glu Glu Leu Val
1 5 10 15
<210>106
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>106
Thr Ser Gly Ser Asp Ser Asp Glu Glu Leu Val Thr Thr Glu Arg
1 5 10 15
<210>107
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>107
Asp Ser Asp Glu Glu Leu Val Thr Thr Glu Arg Lys Thr Pro Arg
1 5 10 15
<210>108
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>108
Glu Leu Val Thr Thr Glu Arg Lys Thr Pro Arg Val Thr Gly Gly
1 5 10 15
<210>109
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>109
Thr Glu Arg Lys Thr Pro Arg Val Thr Gly Gly Gly Ala Met Ala
1 5 10 15
<210>110
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>110
Thr Pro Arg Val Thr Gly Gly Gly Ala Met Ala Gly Ala Ser Thr
1 5 10 15
<210>111
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>111
Thr Gly Gly Gly Ala Met Ala Gly Ala Ser Thr Ser Ala Gly Arg
1 5 10 15
<210>112
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>112
Ala Met Ala Gly Ala Ser Thr Ser Ala Gly Arg Lys Arg Lys Ser
1 5 10 15
<210>113
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>113
Ala Ser Thr Ser Ala Gly Arg Lys Arg Lys Ser Ala Ser Ser Ala
1 5 10 15
<210>114
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>114
Ala Gly Arg Lys Arg Lys Ser Ala Ser Ser Ala Thr Ala Cys Thr
1 5 10 15
<210>115
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>115
Arg Lys Ser Ala Ser Ser Ala Thr Ala Cys Thr Ser Gly Val Met
1 5 10 15
<210>116
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>116
Ser Ser Ala Thr Ala Cys Thr Ser Gly Val Met Thr Arg Gly Arg
1 5 10 15
<210>117
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>117
Ala Cys Thr Ser Gly Val Met Thr Arg Gly Arg Leu Lys Ala Glu
1 5 10 15
<210>118
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>118
Gly Val Met Thr Arg Gly Arg Leu Lys Ala Glu Ser Thr Val Ala
1 5 10 15
<210>119
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>119
Arg Gly Arg Leu Lys Ala Glu Ser Thr Val Ala Pro Glu Glu Asp
1 5 10 15
<210>120
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>120
Lys Ala Glu Ser Thr Val Ala Pro Glu Glu Asp Thr Asp Glu Asp
1 5 10 15
<210>121
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>121
Thr Val Ala Pro Glu Glu Asp Thr Asp Glu Asp Ser Asp Asn Glu
1 5 10 15
<210>122
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>122
Glu Glu Asp Thr Asp Glu Asp Ser Asp Asn Glu Ile His Asn Pro
1 5 10 15
<210>123
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>123
Asp Glu Asp Ser Asp Asn Glu Ile His Asn Pro Ala Val Phe Thr
1 5 10 15
<210>124
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>124
Asp Asn Glu Ile His Asn Pro Ala Val Phe Thr Trp Pro Pro Trp
1 5 10 15
<210>125
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>125
His Asn Pro Ala Val Phe Thr Trp Pro Pro Trp Gln Ala Gly Ile
1 5 10 15
<210>126
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>126
Val Phe Thr Trp Pro Pro Trp Gln Ala Gly Ile Leu Ala Arg Asn
1 5 10 15
<210>127
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>127
Pro Pro Trp Gln Ala Gly Ile Leu Ala Arg Asn Leu Val Pro Met
1 5 10 15
<210>128
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>128
Ala Gly Ile Leu Ala Arg Asn Leu Val Pro Met Val Ala Thr Val
1 5 10 15
<210>129
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>129
Ala Arg Asn Leu Val Pro Met Val Ala Thr Val Gln Gly Gln Asn
1 5 10 15
<210>130
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>130
Val Pro Met Val Ala Thr Val Gln Gly Gln Asn Leu Lys Tyr Gln
1 5 10 15
<210>131
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>131
Ala Thr Val Gln Gly Gln Asn Leu Lys Tyr Gln Glu Phe Phe Trp
1 5 10 15
<210>132
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>132
Gly Gln Asn Leu Lys Tyr Gln Glu Phe Phe Trp Asp Ala Asn Asp
1 5 10 15
<210>133
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>133
Lys Tyr Gln Glu Phe Phe Trp Asp Ala Asn Asp Ile Tyr Arg Ile
1 5 10 15
<210>134
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>134
Phe Phe Trp Asp Ala Asn Asp Ile Tyr Arg Ile Phe Ala Glu Leu
1 5 10 15
<210>135
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>135
Ala Asn AspIle Tyr Arg Ile Phe Ala Glu Leu Glu Gly Val Trp
1 5 10 15
<210>136
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>136
Tyr Arg Ile Phe Ala Glu Leu Glu Gly Val Trp Gln Pro Ala Ala
1 5 10 15
<210>137
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>137
Ala Glu Leu Glu Gly Val Trp Gln Pro Ala Ala Gln Pro Lys Arg
1 5 10 15
<210>138
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>138
Gly Val Trp Gln Pro Ala Ala Gln Pro Lys Arg Arg Arg His Arg
1 5 10 15
<210>139
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>139
Pro Ala Ala Gln Pro Lys Arg Arg Arg His Arg Gln Asp Ala Leu
1 5 10 15
<210>140
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>140
Pro Lys Arg Arg Arg His Arg Gln Asp Ala Leu Pro Gly Pro Cys
1 5 10 15
<210>141
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>141
Arg His Arg Gln Asp Ala Leu Pro Gly Pro Cys Ile Ala Ser Thr
1 5 10 15
<210>142
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>142
Asp Ala Leu Pro Gly Pro Cys Ile Ala Ser Thr Pro Lys Lys His
1 5 10 15
<210>143
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>143
Leu Pro Gly Pro Cys Ile Ala Ser Thr Pro Lys Lys His Arg Gly
1 5 10 15
<210>144
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>144
Met Glu Ser Ser Ala Lys Arg Lys Met Asp Pro Asp Asn Pro Asp
1 5 10 15
<210>145
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>145
Ala Lys Arg Lys Met Asp Pro Asp Asn Pro Asp Glu Gly Pro Ser
1 5 10 15
<210>146
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>146
Met Asp Pro Asp Asn Pro Asp Glu Gly Pro Ser Ser Lys Val Pro
1 5 10 15
<210>147
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>147
Asn Pro Asp Glu Gly Pro Ser Ser Lys Val Pro Arg Pro Glu Thr
1 5 10 15
<210>148
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>148
Gly Pro Ser Ser Lys Val Pro Arg Pro Glu Thr Pro Val Thr Lys
1 5 10 15
<210>149
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>149
Lys Val Pro Arg Pro Glu Thr Pro Val Thr Lys Ala Thr Thr Phe
1 5 10 15
<210>150
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>150
Pro Glu Thr Pro Val Thr Lys Ala Thr Thr Phe Leu Gln Thr Met
1 5 10 15
<210>151
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>151
Val Thr Lys Ala Thr Thr Phe Leu Gln Thr Met Leu Arg Lys Glu
1 5 10 15
<210>152
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>152
Thr Thr Phe Leu Gln Thr Met Leu Arg Lys Glu Val Asn Ser Gln
1 5 10 15
<210>153
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>153
Gln Thr Met Leu Arg Lys Glu Val Asn Ser Gln Leu Ser Leu Gly
1 5 10 15
<210>154
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>154
Arg Lys Glu Val Asn Ser Gln Leu Ser Leu Gly Asp Pro Leu Phe
1 5 10 15
<210>155
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>155
Asn Ser Gln Leu Ser Leu Gly Asp Pro Leu Phe Pro Glu Leu Ala
1 5 10 15
<210>156
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>156
Ser Leu Gly Asp Pro Leu Phe Pro Glu Leu Ala Glu Glu Ser Leu
1 5 10 15
<210>157
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>157
Pro Leu Phe Pro Glu Leu Ala Glu Glu Ser Leu Lys Thr Phe Glu
1 5 10 15
<210>158
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>158
Glu Leu Ala Glu Glu Ser Leu Lys Thr Phe Glu Gln Val Thr Glu
1 5 10 15
<210>159
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>159
Glu Ser Leu Lys Thr Phe Glu Gln Val Thr Glu Asp Cys Asn Glu
1 5 10 15
<210>160
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>160
Thr Phe Glu Gln Val Thr Glu Asp Cys Asn Glu Asn Pro Glu Lys
1 5 10 15
<210>161
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>161
Val Thr Glu Asp Cys Asn Glu Asn Pro Glu Lys Asp Val Leu Ala
1 5 10 15
<210>162
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>162
Cys Asn Glu Asn Pro Glu Lys Asp Val Leu Ala Glu Leu Val Lys
1 5 10 15
<210>163
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>163
Pro Glu Lys Asp Val Leu Ala Glu Leu Val Lys Gln Ile Lys Val
1 5 10 15
<210>164
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>164
Val Leu Ala Glu Leu Val Lys Gln Ile Lys Val Arg Val Asp Met
1 5 10 15
<210>165
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>165
Leu Val Lys Gln Ile Lys Val Arg Val Asp Met Val Arg His Arg
1 5 10 15
<210>166
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>166
Ile Lys Val Arg Val Asp Met Val Arg His Arg Ile Lys Glu His
1 5 10 15
<210>167
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>167
Val Asp Met Val Arg His Arg Ile Lys Glu His Met Leu Lys Lys
1 5 10 15
<210>168
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>168
Arg His Arg Ile Lys Glu His Met Leu Lys Lys Tyr Thr Gln Thr
1 5 10 15
<210>169
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>169
Lys Glu His Met Leu Lys Lys Tyr Thr Gln Thr Glu Glu Lys Phe
1 5 10 15
<210>170
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>170
Leu Lys Lys Tyr Thr Gln Thr Glu Glu Lys Phe Thr Gly Ala Phe
1 5 10 15
<210>171
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>171
Thr Gln Thr Glu Glu Lys Phe Thr Gly Ala Phe Asn Met Met Gly
1 5 10 15
<210>172
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>172
Glu Lys Phe Thr Gly Ala Phe Asn Met Met Gly Gly Cys Leu Gln
1 5 10 15
<210>173
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>173
Gly Ala Phe Asn Met Met Gly Gly Cys Leu Gln Asn Ala Leu Asp
1 5 10 15
<210>174
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>174
Met Met Gly Gly Cys Leu Gln Asn Ala Leu Asp Ile Leu Asp Lys
1 5 10 15
<210>175
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>175
Cys Leu Gln Asn Ala Leu Asp Ile Leu Asp Lys Val His Glu Pro
1 5 10 15
<210>176
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>176
Ala Leu Asp Ile Leu Asp Lys Val His Glu Pro Phe Glu Glu Met
1 5 10 15
<210>177
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>177
Leu Asp Lys Val His Glu Pro Phe Glu Glu Met Lys Cys Ile Gly
1 5 10 15
<210>178
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>178
His Glu Pro Phe Glu Glu Met Lys Cys Ile Gly Leu Thr Met Gln
1 5 10 15
<210>179
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>179
Glu Glu Met Lys Cys Ile Gly Leu Thr Met Gln Ser Met Tyr Glu
1 5 10 15
<210>180
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>180
Cys Ile Gly Leu Thr Met Gln Ser Met Tyr Glu Asn Tyr Ile Val
1 5 10 15
<210>181
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>181
Thr Met Gln Ser Met Tyr Glu Asn Tyr Ile Val Pro Glu Asp Lys
1 5 10 15
<210>182
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>182
Met Tyr Glu Asn Tyr Ile Val Pro Glu Asp Lys Arg Glu Met Trp
1 5 10 15
<210>183
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>183
Tyr Ile Val Pro Glu Asp Lys Arg Glu Met Trp Met Ala Cys Ile
1 5 10 15
<210>184
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>184
Glu Asp Lys Arg Glu Met Trp Met Ala Cys Ile Lys Glu Leu His
1 5 10 15
<210>185
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>185
Glu Met Trp Met Ala Cys Ile Lys Glu Leu His Asp Val Ser Lys
1 5 10 15
<210>186
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>186
Ala Cys Ile Lys Glu Leu His Asp Val Ser Lys Gly Ala Ala Asn
1 5 10 15
<210>187
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>187
Glu Leu His Asp Val Ser Lys Gly Ala Ala Asn Lys Leu Gly Gly
1 5 10 15
<210>188
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>188
Val Ser Lys Gly Ala Ala Asn Lys Leu Gly Gly Ala Leu Gln Ala
1 5 10 15
<210>189
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>189
Ala Ala Asn Lys Leu Gly Gly Ala Leu Gln Ala Lys Ala Arg Ala
1 5 10 15
<210>190
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>190
Leu Gly Gly Ala Leu Gln Ala Lys Ala Arg Ala Lys Lys Asp Glu
1 5 10 15
<210>191
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>191
Leu Gln Ala Lys Ala Arg Ala Lys Lys Asp Glu Leu Arg Arg Lys
1 5 10 15
<210>192
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>192
Ala Arg Ala Lys Lys Asp Glu Leu Arg Arg Lys Met Met Tyr Met
1 5 10 15
<210>193
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>193
Lys Asp Glu Leu Arg Arg Lys Met Met Tyr Met Cys Tyr Arg Asn
1 5 10 15
<210>194
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>194
Arg Arg Lys Met Met Tyr Met Cys Tyr Arg Asn Ile Glu Phe Phe
1 5 10 15
<210>195
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>195
Met Tyr Met Cys Tyr Arg Asn Ile Glu Phe Phe Thr Lys Asn Ser
1 5 10 15
<210>196
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>196
Tyr Arg Asn Ile Glu Phe Phe Thr Lys Asn Ser Ala Phe Pro Lys
1 5 10 15
<210>197
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>197
Glu Phe Phe Thr Lys Asn Ser Ala Phe Pro Lys Thr Thr Asn Gly
1 5 10 15
<210>198
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>198
Lys Asn Ser Ala Phe Pro Lys Thr Thr Asn Gly Cys Ser Gln Ala
1 5 10 15
<210>199
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>199
Phe Pro Lys Thr Thr Asn Gly Cys Ser Gln Ala Met Ala Ala Leu
1 5 10 15
<210>200
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>200
Thr Asn Gly Cys Ser Gln Ala Met Ala Ala Leu Gln Asn Leu Pro
1 5 10 15
<210>201
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>201
Ser Gln Ala Met Ala Ala Leu Gln Asn Leu Pro Gln Cys Ser Pro
1 5 10 15
<210>202
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>202
Ala Ala Leu Gln Asn Leu Pro Gln Cys Ser Pro Asp Glu Ile Met
1 5 10 15
<210>203
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>203
Asn Leu Pro Gln Cys Ser Pro Asp Glu Ile Met Ala Tyr Ala Gln
1 5 10 15
<210>204
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>204
Cys Ser Pro Asp Glu Ile Met Ala Tyr Ala Gln Lys Ile Phe Lys
1 5 10 15
<210>205
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>205
Glu Ile Met Ala Tyr Ala Gln Lys Ile Phe Lys Ile Leu Asp Glu
1 5 10 15
<210>206
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>206
Tyr Ala Gln Lys Ile Phe Lys Ile Leu Asp Glu Glu Arg Asp Lys
1 5 10 15
<210>207
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>207
Ile Phe Lys Ile Leu Asp Glu Glu Arg Asp Lys Val Leu Thr His
1 5 10 15
<210>208
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>208
Leu Asp Glu Glu Arg Asp Lys Val Leu Thr His Ile Asp His Ile
1 5 10 15
<210>209
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>209
Arg Asp Lys Val Leu Thr His Ile Asp His Ile Phe Met Asp Ile
1 5 10 15
<210>210
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>210
Leu Thr HisIle Asp His Ile Phe Met Asp Ile Leu Thr Thr Cys
1 5 10 15
<210>211
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>211
Asp His Ile Phe Met Asp Ile Leu Thr Thr Cys Val Glu Thr Met
1 5 10 15
<210>212
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>212
Met Asp Ile Leu Thr Thr Cys Val Glu Thr Met Cys Asn Glu Tyr
1 5 10 15
<210>213
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>213
Thr Thr Cys Val Glu Thr Met Cys Asn Glu Tyr Lys Val Thr Ser
1 5 10 15
<210>214
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>214
Glu Thr Met Cys Asn Glu Tyr Lys Val Thr Ser Asp Ala Cys Met
1 5 10 15
<210>215
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>215
Asn Glu Tyr Lys Val Thr Ser Asp Ala Cys Met Met Thr Met Tyr
1 5 10 15
<210>216
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>216
Val Thr Ser Asp Ala Cys Met Met Thr Met Tyr Gly Gly Ile Ser
1 5 10 15
<210>217
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>217
Ala Cys Met Met Thr Met Tyr Gly Gly Ile Ser Leu Leu Ser Glu
1 5 10 15
<210>218
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>218
Thr Met Tyr Gly Gly Ile Ser Leu Leu Ser Glu Phe Cys Arg Val
1 5 10 15
<210>219
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>219
Gly Ile Ser Leu Leu Ser Glu Phe Cys Arg Val Leu Cys Cys Tyr
1 5 10 15
<210>220
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>220
Leu Ser Glu Phe Cys Arg Val Leu Cys Cys Tyr Val Leu Glu Glu
1 5 10 15
<210>221
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>221
Cys Arg Val Leu Cys Cys Tyr Val Leu Glu Glu Thr Ser Val Met
1 5 10 15
<210>222
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>222
Cys Cys Tyr Val Leu Glu Glu Thr Ser Val Met Leu Ala Lys Arg
1 5 10 15
<210>223
<211>15
<212>PRT
<213>Artificial
<220>
<223>Hunan cytomegalovirus
<400>223
Leu Glu Glu Thr Ser Val Met Leu Ala Lys Arg Pro Leu Ile Thr
1 5 10 15
<210>224
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>224
Ser Val Met Leu Ala Lys Arg Pro Leu Ile Thr Lys Pro Glu Val
1 5 10 15
<210>225
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>225
Ala Lys Arg Pro Leu Ile Thr Lys Pro Glu Val Ile Ser Val Met
1 5 10 15
<210>226
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>226
Leu Ile Thr Lys Pro Glu Val Ile Ser Val Met Lys Arg Arg Ile
1 5 10 15
<210>227
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>227
Pro Glu Val Ile Ser Val Met Lys Arg Arg Ile Glu Glu Ile Cys
1 5 10 15
<210>228
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegal ovirus
<400>228
Ser Val Met Lys Arg Arg Ile Glu Glu Ile Cys Met Lys Val Phe
1 5 10 15
<210>229
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>229
Arg Arg Ile Glu Glu Ile Cys Met Lys Val Phe Ala Gln Tyr Ile
1 5 10 15
<210>230
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>230
Glu Ile Cys Met Lys Val Phe Ala Gln Tyr Ile Leu Gly Ala Asp
1 5 10 15
<210>231
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>231
Lys Val Phe Ala Gln Tyr Ile Leu Gly Ala Asp Pro Leu Arg Val
1 5 10 15
<210>232
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>232
Gln Tyr Ile Leu Gly Ala Asp Pro Leu Arg Val Cys Ser Pro Ser
1 5 10 15
<210>233
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>233
Gly Ala Asp Pro Leu Arg Val Cys Ser Pro Ser Val Asp Asp Leu
1 5 10 15
<210>234
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>234
Leu Arg Val Cys Ser Pro Ser Val Asp Asp Leu Arg Ala Ile Ala
1 5 10 15
<210>235
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>235
Ser Pro Ser Val Asp Asp Leu Arg Ala Ile Ala Glu Glu Ser Asp
1 5 10 15
<210>236
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>236
Asp Asp Leu Arg Ala Ile Ala Glu Glu Ser Asp Glu Glu Glu Ala
1 5 10 15
<210>237
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>237
Ala Ile Ala Glu Glu Ser Asp Glu Glu Glu Ala Ile Val Ala Tyr
1 5 10 15
<210>238
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>238
Glu Ser Asp Glu Glu Glu Ala Ile Val Ala Tyr Thr Leu Ala Thr
1 5 10 15
<210>239
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>239
Glu Glu Ala Ile Val Ala Tyr Thr Leu Ala Thr Ala Gly Val Ser
1 5 10 15
<210>240
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>240
Val Ala Tyr Thr Leu Ala Thr Ala Gly Val Ser Ser Ser Asp Ser
1 5 10 15
<210>241
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>241
Leu Ala Thr Ala Gly Val Ser Ser Ser Asp Ser Leu Val Ser Pro
1 5 10 15
<210>242
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>242
Gly Val Ser Ser Ser Asp Ser Leu Val Ser Pro Pro Glu Ser Pro
1 5 10 15
<210>243
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>243
Ser Asp Ser Leu Val Ser Pro Pro Glu Ser Pro Val Pro Ala Thr
1 5 10 15
<210>244
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>244
Val Ser Pro Pro Glu Ser Pro Val Pro Ala Thr Ile Pro Leu Ser
1 5 10 15
<210>245
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>245
Glu Ser Pro Val Pro Ala Thr Ile Pro Leu Ser Ser Val Ile Val
1 5 10 15
<210>246
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>246
Pro Ala Thr Ile Pro Leu Ser Ser Val Ile Val Ala Glu Asn Ser
1 5 10 15
<210>247
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>247
Pro Leu Ser Ser Val Ile Val Ala Glu Asn Ser Asp Gln Glu Glu
1 5 10 15
<210>248
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>248
Val Ile Val Ala Glu Asn Ser Asp Gln Glu Glu Ser Glu Gln Ser
1 5 10 15
<210>249
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>249
Glu Asn Ser Asp Gln Glu Glu Ser Glu Gln Ser Asp Glu Glu Glu
1 5 10 15
<210>250
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>250
Gln Glu Glu Ser Glu Gln Ser Asp Glu Glu Glu Glu Glu Gly Ala
1 5 10 15
<210>251
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>251
Glu Gln Ser Asp Glu Glu Glu Glu Glu Gly Ala Gln Glu Glu Arg
1 5 10 15
<210>252
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>252
Glu Glu Glu Glu Glu Gly Ala Gln Glu Glu Arg Glu Asp Thr Val
1 5 10 15
<210>253
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>253
Glu Gly Ala Gln Glu Glu Arg Glu Asp Thr Val Ser Val Lys Ser
1 5 10 15
<210>254
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>254
Glu Glu Arg Glu Asp Thr Val Ser Val Lys Ser Glu Pro Val Ser
1 5 10 15
<210>255
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>255
Asp Thr Val Ser Val Lys Ser Glu Pro Val Ser Glu Ile Glu Glu
1 5 10 15
<210>256
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>256
Val Lys Ser Glu Pro Val Ser Glu Ile Glu Glu Val Ala Pro Glu
1 5 10 15
<210>257
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>257
Pro Val Ser Glu Ile Glu Glu Val Ala Pro Glu Glu Glu Glu Asp
1 5 10 15
<210>258
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>258
Ile Glu Glu Val Ala Pro Glu Glu Glu Glu Asp Gly Ala Glu Glu
1 5 10 15
<210>259
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>259
Ala Pro Glu Glu Glu Glu Asp Gly Ala Glu Glu Pro Thr Ala Ser
1 5 10 15
<210>260
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>260
Glu Glu Asp Gly Ala Glu Glu Pro Thr Ala Ser Gly Gly Lys Ser
1 5 10 15
<210>261
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>261
Ala Glu Glu Pro Thr Ala Ser Gly Gly Lys Ser Thr His Pro Met
1 5 10 15
<210>262
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>262
Thr Ala Ser Gly Gly Lys Ser Thr His Pro Met Val Thr Arg Ser
1 5 10 15
<210>263
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>263
Gly Lys Ser Thr His Pro Met Val Thr Arg Ser Lys Ala Asp Gln
1 5 10 15
<210>264
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>264
Met Glu Ser Arg Ile Trp Cys Leu Val Val Cys Val Asn Leu Cys
1 5 10 15
<210>265
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>265
Ile Trp Cys Leu Val Val Cys Val Asn Leu Cys Ile Val Cys Leu
1 5 10 15
<210>266
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>266
Val Val Cys Val Asn Leu Cys Ile Val Cys Leu Gly Ala Ala Val
1 5 10 15
<210>267
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>267
Asn Leu Cys Ile Val Cys Leu Gly Ala Ala Val Ser Ser Ser Ser
1 5 10 15
<210>268
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>268
Val Cys Leu Gly Ala Ala Val Ser Ser Ser Ser Thr Arg Gly Thr
1 5 10 15
<210>269
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>269
Ala Ala Val Ser Ser Ser Ser Thr Arg Gly Thr Ser Ala Thr His
1 5 10 15
<210>270
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>270
Ser Ser Ser Thr Arg Gly Thr Ser Ala Thr His Ser His His Ser
1 5 10 15
<210>271
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>271
Arg Gly Thr Ser Ala Thr His Ser His His Ser Ser His Thr Thr
1 5 10 15
<210>272
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>272
Ala Thr His Ser His His Ser Ser His Thr Thr Ser Ala Ala His
1 5 10 15
<210>273
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>273
His His Ser Ser His Thr Thr Ser Ala Ala His Ser Arg Ser Gly
1 5 10 15
<210>274
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>274
His Thr Thr Ser Ala Ala His Ser Arg Ser Gly Ser Val Ser Gln
1 5 10 15
<210>275
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>275
Ala Ala His Ser Arg Ser Gly Ser Val Ser Gln Arg Val Thr Ser
1 5 10 15
<210>276
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>276
Arg Ser Gly Ser Val Ser Gln Arg Val Thr Ser Ser Gln Thr Val
1 5 10 15
<210>277
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>277
Val Ser Gln Arg Val Thr Ser Ser Gln Thr Val Ser His Gly Val
1 5 10 15
<210>278
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>278
Val Thr Ser Ser Gln Thr Val Ser His Gly Val Asn Glu Thr Ile
1 5 10 15
<210>279
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>279
Gln Thr Val Ser His Gly Val Asn Glu Thr Ile Tyr Asn Thr Thr
1 5 10 15
<210>280
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>280
His Gly Val Asn Glu Thr Ile Tyr Asn Thr Thr Leu Lys Tyr Gly
1 5 10 15
<210>281
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>281
Glu Thr Ile Tyr Asn Thr Thr Leu Lys Tyr Gly Asp Val Val Gly
1 5 10 15
<210>282
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>282
Asn Thr Thr Leu Lys Tyr Gly Asp Val Val Gly Val Asn Thr Thr
1 5 10 15
<210>283
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>283
Lys Tyr Gly Asp Val Val Gly Val Asn Thr Thr Lys Tyr Pro Tyr
1 5 10 15
<210>284
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>284
Val Val Gly Val Asn Thr Thr Lys Tyr Pro Tyr Arg Val Cys Ser
1 5 10 15
<210>285
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>285
Asn Thr Thr Lys Tyr Pro Tyr Arg Val Cys Ser Met Ala Gln Gly
1 5 10 15
<210>286
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>286
Tyr Pro Tyr Arg Val Cys Ser Met Ala Gln Gly Thr Asp Leu Ile
1 5 10 15
<210>287
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>287
Val Cys Ser Met Ala Gln Gly Thr Asp Leu Ile Arg Phe Glu Arg
1 5 10 15
<210>288
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>288
Ala Gln Gly Thr Asp Leu Ile Arg Phe Glu Arg Asn Ile Val Cys
1 5 10 15
<210>289
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>289
Asp Leu Ile Arg Phe Glu Arg Asn Ile Val Cys Thr Ser Met Lys
1 5 10 15
<210>290
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>290
Phe Glu Arg Asn Ile Val Cys Thr Ser Met Lys Pro Ile Asn Glu
1 5 10 15
<210>291
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>291
Ile Val Cys Thr Ser Met Lys Pro Ile Asn Glu Asp Leu Asp Glu
1 5 10 15
<210>292
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>292
Ser Met Lys Pro Ile Asn Glu Asp Leu Asp Glu Gly Ile Met Val
1 5 10 15
<210>293
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>293
Ile Asn Glu Asp Leu Asp Glu Gly Ile Met Val Val Tyr Lys Arg
1 5 10 15
<210>294
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>294
Leu Asp Glu Gly Ile Met Val Val Tyr Lys Arg AsnIle Val Ala
1 5 10 15
<210>295
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>295
Ile Met Val Val Tyr Lys Arg Asn Ile Val Ala His Thr Phe Lys
1 5 10 15
<210>296
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>296
Tyr Lys Arg Asn Ile Val Ala His Thr Phe Lys Val Arg Val Tyr
1 5 10 15
<210>297
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>297
Ile Val Ala His Thr Phe Lys Val Arg Val Tyr Gln Lys Val Leu
1 5 10 15
<210>298
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>298
Thr Phe Lys Val Arg Val Tyr Gln Lys Val Leu Thr Phe Arg Arg
1 5 10 15
<210>299
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>299
Arg Val Tyr Gln Lys Val Leu Thr Phe Arg Arg Ser Tyr Ala Tyr
1 5 10 15
<2l0>300
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>300
Lys Val Leu Thr Phe Arg Arg Ser Tyr Ala Tyr Ile His Thr Thr
1 5 10 15
<210>301
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>301
Phe Arg Arg Ser Tyr Ala Tyr Ile His Thr Thr Tyr Leu Leu Gly
1 5 10 15
<210>302
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>302
Tyr Ala Tyr Ile His Thr Thr Tyr Leu Leu Gly Ser Asn Thr Glu
1 5 10 15
<210>303
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>303
His Thr Thr Tyr Leu Leu Gly Ser Asn Thr Glu Tyr Val Ala Pro
1 5 10 15
<210>304
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>304
Leu Leu Gly Ser Asn Thr Glu Tyr Val Ala Pro Pro Met Trp Glu
1 5 10 15
<210>305
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>305
Asn Thr Glu Tyr Val Ala Pro Pro Met Trp Glu Ile His His Ile
1 5 10 15
<210>306
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>306
Val Ala Pro Pro Met Trp Glu Ile His His Ile Asn Ser His Ser
1 5 10 15
<210>307
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>307
Met Trp Glu Ile His His Ile Asn Ser His Ser Gln Cys Tyr Ser
1 5 10 15
<210>308
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>308
His His Ile Asn Ser His Ser Gln Cys Tyr Ser Ser Tyr Ser Arg
1 5 10 15
<210>309
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>309
Ser His Ser Gln Cys Tyr Ser Ser Tyr Ser Arg Val Ile Ala Gly
1 5 10 15
<210>310
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>310
Cys Tyr Ser Ser Tyr Ser Arg Val Ile Ala Gly Thr Val Phe Val
1 5 10 15
<210>311
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>311
Tyr Ser Arg Val Ile Ala Gly Thr Val Phe Val Ala Tyr His Arg
1 5 10 15
<210>312
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>312
Ile Ala Gly Thr Val Phe Val Ala Tyr His Arg Asp Ser Tyr Glu
1 5 10 15
<210>313
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>313
Val Phe Val Ala Tyr His Arg Asp Ser Tyr Glu Asn Lys Thr Met
1 5 10 15
<210>314
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>314
Tyr His Arg Asp Ser Tyr Glu Asn Lys Thr Met Gln Leu Met Pro
1 5 10 15
<210>315
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>315
Ser Tyr Glu Asn Lys Thr Met Gln Leu Met Pro Asp Asp Tyr Ser
1 5 10 15
<210>316
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegal ovirus
<400>316
Lys Thr Met Gln Leu Met Pro Asp Asp Tyr Ser Asn Thr His Ser
1 5 10 15
<210>317
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>317
Leu Met Pro Asp Asp Tyr Ser Asn Thr His Ser Thr Arg Tyr Val
1 5 10 15
<210>318
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>318
Asp Tyr Ser Asn Thr His Ser Thr Arg Tyr Val Thr Val Lys Asp
1 5 10 15
<210>319
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>319
Thr His Ser Thr Arg Tyr Val Thr Val Lys Asp Gln Trp His Ser
151015
<210>320
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>320
Arg Tyr Val Thr Val Lys Asp Gln Trp His Ser Arg Gly Ser Thr
1 5 10 15
<210>321
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>321
Val Lys Asp Gln Trp His Ser Arg Gly Ser Thr Trp Leu Tyr Arg
1 5 10 15
<210>322
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>322
Trp His Ser Arg Gly Ser Thr Trp Leu Tyr Arg Glu Thr Cys Asn
1 5 10 15
<210>323
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>323
Gly Ser Thr Trp Leu Tyr Arg Glu Thr Cys Asn Leu Asn Cys Met
1 5 10 15
<210>324
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>324
Leu Tyr Arg Glu Thr Cys Asn Leu Asn Cys Met Val Thr Ile Thr
1 5 10 15
<210>325
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>325
Thr Cys Asn Leu Asn Cys Met Val Thr Ile Thr Thr Ala Arg Ser
1 5 10 15
<210>326
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>326
Asn Cys Met Val Thr Ile Thr Thr Ala Arg Ser Lys Tyr Pro Tyr
1 5 10 15
<210>327
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>327
Thr Ile Thr Thr Ala Arg Ser Lys Tyr Pro Tyr His Phe Phe Ala
1 5 10 15
<210>328
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>328
Ala Arg Ser Lys Tyr Pro Tyr His Phe Phe Ala Thr Ser Thr Gly
1 5 10 15
<210>329
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>329
Tyr Pro Tyr His Phe Phe Ala Thr Ser Thr Gly Asp Val Val Asp
1 5 10 15
<210>330
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>330
Phe Phe Ala Thr Ser Thr Gly Asp Val Val Asp Ile Ser Pro Phe
1 5 10 15
<210>331
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>331
Ser Thr Gly Asp Val Val Asp Ile Ser Pro Phe Tyr Asn Gly Thr
1 5 10 15
<210>332
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>332
Val Val Asp Ile Ser Pro Phe Tyr Asn Gly Thr Asn Arg Asn Ala
1 5 10 15
<210>333
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>333
Ser Pro Phe Tyr Asn Gly Thr Asn Arg Asn Ala Ser Tyr Phe Gly
1 5 10 15
<210>334
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>334
Asn Gly Thr Asn Arg Asn Ala Ser Tyr Phe Gly Glu Asn Ala Asp
1 5 10 15
<210>335
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>335
Arg Asn Ala Ser Tyr Phe Gly Glu Asn Ala Asp Lys Phe Phe Ile
1 5 10 15
<210>336
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>336
Tyr Phe Gly Glu Asn Ala Asp Lys Phe Phe Ile Phe Pro Asn Tyr
1 5 10 15
<210>337
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>337
Asn Ala Asp Lys Phe Phe Ile Phe Pro Asn Tyr Thr Ile Val Ser
1 5 10 15
<210>338
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>338
Phe Phe Ile Phe Pro Asn Tyr Thr Ile Val Ser Asp Phe Gly Arg
1 5 10 15
<210>339
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>339
Pro Asn Tyr Thr Ile Val Ser Asp Phe Gly Arg Pro Asn Ser Ala
1 5 10 15
<210>340
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>340
Ile Val Ser Asp Phe Gly Arg Pro Asn Ser Ala Leu Glu Thr His
1 5 10 15
<210>341
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>341
Phe Gly Arg Pro Asn Ser Ala Leu Glu Thr His Arg Leu Val Ala
1 5 10 15
<210>342
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>342
Asn Ser Ala Leu Glu Thr His Arg Leu Val Ala Phe Leu Glu Arg
1 5 10 15
<210>343
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>343
Glu Thr His Arg Leu Val Ala Phe Leu Glu Arg Ala Asp Ser Val
1 5 10 15
<210>344
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>344
Leu Val Ala Phe Leu Glu Arg Ala Asp Ser Val Ile Ser Trp Asp
1 5 10 15
<210>345
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>345
Leu Glu Arg Ala Asp Ser Val Ile Ser Trp Asp Ile Gln Asp Glu
1 5 10 15
<210>346
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>346
Asp Ser Val Ile Ser Trp Asp Ile Gln Asp Glu Lys Asn Val Thr
1 5 10 15
<210>347
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>347
Ser Trp Asp Ile Gln Asp Glu Lys Asn Val Thr Cys Gln Leu Thr
1 5 10 15
<210>348
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>348
Gln Asp Glu Lys Asn Val Thr Cys Gln Leu Thr Phe Trp Glu Ala
1 5 10 15
<210>349
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>349
Asn Val Thr Cys Gln Leu Thr Phe Trp Glu Ala Ser Glu Arg Thr
1 5 10 15
<210>350
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>350
Gln Leu Thr Phe Trp Glu Ala Ser Glu Arg Thr Ile Arg Ser Glu
1 5 10 15
<210>351
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>351
Trp Glu Ala Ser Glu Arg ThrIle Arg Ser Glu Ala Glu Asp Ser
1 5 10 15
<210>352
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>352
Glu Arg Thr Ile Arg Ser Glu A1a Glu Asp Ser Tyr His Phe Ser
1 5 10 15
<210>353
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>353
Arg Ser Glu Ala Glu Asp Ser Tyr His Phe Ser Ser Ala Lys Met
1 5 10 15
<210>354
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>354
Glu Asp Ser Tyr His Phe Ser Ser Ala Lys Met Thr Ala Thr Phe
1 5 10 15
<210>355
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>355
His Phe Ser Ser Ala Lys Met Thr Ala Thr Phe Leu Ser Lys Lys
1 5 10 15
<210>356
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>356
Ala Lys Met Thr Ala Thr Phe Leu Ser Lys Lys Gln Glu Val Asn
1 5 10 15
<210>357
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>357
Ala Thr Phe Leu Ser Lys Lys Gln Glu Val Asn Met Ser Asp Ser
1 5 10 15
<210>358
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>358
Ser Lys Lys Gln Glu Val Asn Met Ser Asp Ser Ala Leu Asp Cys
1 5 10 15
<210>359
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>359
Glu Val Asn Met Ser Asp Ser Ala Leu Asp Cys Val Arg Asp Glu
1 5 10 15
<210>360
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>360
Ser Asp Ser Ala Leu Asp Cys Val Arg Asp Glu Ala Ile Asn Lys
1 5 10 15
<210>361
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>361
Leu Asp Cys Val Arg Asp Glu Ala Ile Asn Lys Leu Gln Gln Ile
1 5 10 15
<210>362
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>362
Arg Asp Glu Ala Ile Asn Lys Leu Gln Gln Ile Phe Asn Thr Ser
1 5 10 15
<210>363
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>363
Ile Asn Lys Leu Gln Gln Ile Phe Asn Thr Ser Tyr Asn Gln Thr
1 5 10 15
<210>364
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>364
Gln Gln Ile Phe Asn Thr Ser Tyr Asn Gln Thr Tyr Glu Lys Tyr
1 5 10 15
<210>365
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>365
Asn Thr Ser Tyr Asn Gln Thr Tyr Glu Lys Tyr Gly Asn Val Ser
1 5 10 15
<210>366
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>366
Asn Gln Thr Tyr Glu Lys Tyr Gly Asn Val Ser Val Phe Glu Thr
1 5 10 15
<210>367
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>367
Glu Lys Tyr Gly Asn Val Ser Val Phe Glu Thr Thr Gly Gly Leu
1 5 10 15
<210>368
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>368
Asn Val Ser Val Phe Glu Thr Thr Gly Gly Leu Val Val Phe Trp
1 5 10 15
<210>369
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>369
Phe Glu Thr Thr Gly Gly Leu Val Val Phe Trp Gln Gly Ile Lys
1 5 10 15
<210>370
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>370
Gly Gly Leu Val Val Phe Trp Gln Gly Ile Lys Gln Lys Ser Leu
1 5 10 15
<210>371
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>371
Val Phe Trp Gln Gly Ile Lys Gln Lys Ser Leu Val Glu Leu Glu
1 5 10 15
<210>372
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>372
Gly Ile Lys Gln Lys Ser Leu Val Glu Leu Glu Arg Leu Ala Asn
1 5 10 15
<210>373
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>373
Lys Ser Leu Val Glu Leu Glu Arg Leu Ala Asn Arg Ser Ser Leu
1 5 10 15
<210>374
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>374
Glu Leu Glu Arg Leu Ala Asn Arg Ser Ser Leu Asn Leu Thr His
1 5 10 15
<210>375
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>375
Leu Ala Asn Arg Ser Ser Leu Asn Leu Thr His Asn Arg Thr Lys
1 5 10 15
<210>376
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>376
Ser Ser Leu Asn Leu Thr His Asn Arg Thr Lys Arg Ser Thr Asp
1 5 10 15
<210>377
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>377
Leu Thr His Asn Arg Thr Lys Arg Ser Thr Asp Gly Asn Asn Ala
1 5 10 15
<210>378
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>378
Arg Thr Lys Arg Ser Thr Asp Gly Asn Asn Ala Thr His Leu Ser
1 5 10 15
<210>379
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>379
Ser Thr Asp Gly Asn Asn Ala Thr His Leu Ser Asn Met Glu Ser
1 5 10 15
<210>380
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>380
Asn Asn Ala Thr His Leu Ser Asn Met Glu Ser Val His Asn Leu
1 5 10 15
<210>381
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>381
His Leu Ser Asn Met Glu Ser Val His Asn Leu Val Tyr Ala Gln
1 5 10 15
<210>382
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>382
Met Glu Ser Val His Asn Leu Val Tyr Ala Gln Leu Gln Phe Thr
1 5 10 15
<210>383
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>383
His Asn Leu Val Tyr Ala Gln Leu Gln Phe Thr Tyr Asp Thr Leu
1 5 10 15
<210>384
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>384
Tyr Ala Gln Leu Gln Phe Thr Tyr Asp Thr Leu Arg Gly Tyr Ile
1 5 10 15
<210>385
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>385
Gln Phe Thr Tyr Asp Thr Leu Arg Gly Tyr Ile Asn Arg Ala Leu
1 5 10 15
<210>386
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>386
Asp Thr Leu Arg Gly Tyr Ile Asn Arg Ala Leu Ala Gln Ile Ala
1 5 10 15
<210>387
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>387
Gly Tyr Ile Asn Arg Ala Leu Ala Gln Ile Ala Glu Ala Trp Cys
1 5 10 15
<210>388
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>388
Arg Ala Leu Ala Gln Ile Ala Glu Ala Trp Cys Val Asp Gln Arg
1 5 10 15
<210>389
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>389
Gln Ile Ala Glu Ala Trp Cys Val Asp Gln Arg Arg Thr Leu Glu
1 5 10 15
<210>390
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>390
Ala Trp Cys Val Asp Gln Arg Arg Thr Leu Glu Val Phe Lys Glu
1 5 10 15
<210>391
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>391
Asp Gln Arg Arg Thr Leu Glu Val Phe Lys Glu Leu Ser Lys Ile
1 5 10 15
<210>392
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>392
Thr Leu Glu Val Phe Lys Glu Leu Ser Lys Ile Asn Pro Ser Ala
1 5 10 15
<210>393
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>393
Phe Lys Glu Leu Ser Lys Ile Asn Pro Ser Ala Ile Leu Ser Ala
1 5 10 15
<210>394
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>394
Ser Lys Ile Asn Pro Ser Ala Ile Leu Ser Ala Ile Tyr Asn Lys
1 5 10 15
<210>395
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>395
Pro Ser Ala Ile Leu Ser Ala Ile Tyr Asn Lys Pro Ile Ala Ala
1 5 10 15
<210>396
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>396
Leu Ser Ala Ile Tyr Asn Lys Pro Ile Ala Ala Arg Phe Met Gly
1 5 10 15
<210>397
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>397
Tyr Asn Lys Pro Ile Ala Ala Arg Phe Met Gly Asp Val Leu Gly
1 5 10 15
<210>398
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>398
Ile Ala Ala Arg Phe Met Gly Asp Val Leu Gly Leu Ala Ser Cys
1 5 10 15
<210>399
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>399
Phe Met Gly Asp Val Leu Gly Leu Ala Ser Cys Val Thr Ile Asn
1 5 10 15
<210>400
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>400
Val Leu Gly Leu Ala Ser Cys Val Thr Ile Asn Gln Thr Ser Val
1 5 10 15
<210>401
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>401
Ala Ser Cys Val Thr Ile Asn Gln Thr Ser Val Lys Val Leu Arg
1 5 10 15
<210>402
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>402
Thr Ile Asn Gln Thr Ser Val Lys Val Leu Arg Asp Met Asn Val
1 5 10 15
<210>403
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>403
Thr Ser Val Lys Val Leu Arg Asp Met Asn Val Lys Glu Ser Pro
1 5 10 15
<210>404
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>404
Val Leu Arg Asp Met Asn Val Lys Glu Ser Pro Gly Arg Cys Tyr
1 5 10 15
<210>405
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>405
Met Asn Val Lys Glu Ser Pro Gly Arg Cys Tyr Ser Arg Pro Val
1 5 10 15
<210>406
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>406
Glu Ser Pro Gly Arg Cys Tyr Ser Arg Pro Val Val Ile Phe Asn
1 5 10 15
<210>407
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>407
Arg Cys Tyr Ser Arg Pro Val Val Ile Phe Asn Phe Ala Asn Ser
1 5 10 15
<210>408
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>408
Arg Pro Val Val Ile Phe Asn Phe Ala Asn Ser Ser Tyr Val Gln
1 5 10 15
<210>409
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>409
Ile Phe Asn Phe Ala Asn Ser Ser Tyr Val Gln Tyr Gly Gln Leu
1 5 10 15
<210>410
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>410
Ala Asn Ser Ser Tyr Val Gln Tyr Gly Gln Leu Gly Glu Asp Asn
1 5 10 15
<210>411
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>411
Tyr Val Gln Tyr Gly Gln Leu Gly Glu Asp Asn Glu Ile Leu Leu
1 5 10 15
<210>412
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>412
Gly Gln Leu Gly Glu Asp Asn Glu Ile Leu Leu Gly Asn His Arg
1 5 10 15
<210>413
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>413
Glu Asp Asn GluIle Leu Leu Gly Asn His Arg Thr Glu Glu Cys
1 5 10 15
<210>414
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>414
Ile Leu Leu Gly Asn His Arg Thr Glu Glu Cys Gln Leu Pro Ser
1 5 10 15
<210>415
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>415
Asn His Arg Thr Glu Glu Cys Gln Leu Pro Ser Leu LysIle Phe
1 5 10 15
<210>416
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>416
Glu Glu Cys Gln Leu Pro Ser Leu Lys Ile Phe Ile Ala Gly Asn
1 5 10 15
<210>417
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>417
Leu Pro Ser Leu Lys Ile Phe Ile Ala Gly Asn Ser Ala Tyr Glu
1 5 10 15
<210>418
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>418
Lys Ile Phe Ile Ala Gly Asn Ser Ala Tyr Glu Tyr Val Asp Tyr
1 5 10 15
<210>419
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>419
Ala Gly Asn Ser Ala Tyr Glu Tyr Val Asp Tyr Leu Phe Lys Arg
1 5 10 15
<210>420
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>420
Ala Tyr Glu Tyr Val Asp Tyr Leu Phe Lys Arg Met Ile Asp Leu
1 5 10 15
<210>421
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>421
Val Asp Tyr Leu Phe Lys Arg Met Ile Asp Leu Ser Ser Ile Ser
1 5 10 15
<210>422
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>422
Phe Lys Arg Met Ile Asp Leu Ser Ser Ile Ser Thr Val Asp Ser
1 5 10 15
<210>423
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>423
Ile Asp Leu Ser Ser Ile Ser Thr Val Asp Ser Met Ile Ala Leu
1 5 10 15
<210>424
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>424
Ser Ile Ser Thr Val Asp Ser Met Ile Ala Leu Asp Ile Asp Pro
1 5 10 15
<210>425
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>425
Val Asp Ser Met Ile Ala Leu AspIle Asp Pro Leu Glu Asn Thr
1 5 10 15
<210>426
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>426
Ile Ala Leu AspIle Asp Pro Leu Glu Asn Thr Asp Phe Arg Val
1 5 10 15
<210>427
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>427
Ile Asp Pro Leu Glu Asn Thr Asp Phe Arg Val Leu Glu Leu Tyr
1 5 10 15
<210>428
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>428
Glu Asn Thr Asp Phe Arg Val Leu Glu Leu Tyr Ser Gln Lys Glu
1 5 10 15
<210>429
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>429
Phe Arg Val Leu Glu Leu Tyr Ser Gln Lys Glu Leu Arg Ser Ser
1 5 10 15
<210>430
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>430
Glu Leu Tyr Ser Gln Lys Glu Leu Arg Ser Ser Asn Val Phe Asp
1 5 10 15
<210>431
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>431
Gln Lys Glu Leu Arg Ser Ser Asn Val Phe Asp Leu Glu Glu Ile
1 5 10 15
<210>432
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>432
Arg Ser Ser Asn Val Phe Asp Leu Glu Glu Ile Met Arg Glu Phe
1 5 10 15
<210>433
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>433
Val Phe Asp Leu Glu Glu Ile Met Arg Glu Phe Asn Ser Tyr Lys
1 5 10 15
<210>434
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>434
Glu Glu Ile Met Arg Glu Phe Asn Ser Tyr Lys Gln Arg Val Lys
1 5 10 15
<210>435
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>435
Arg Glu Phe Asn Ser Tyr Lys Gln Arg Val Lys Tyr Val Glu Asp
1 5 10 15
<210>436
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>436
Ser Tyr Lys Gln Arg Val Lys Tyr Val Glu Asp Lys Val Val Asp
1 5 10 15
<210>437
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>437
Arg Val Lys Tyr Val Glu Asp Lys Val Val Asp Pro Leu Pro Pro
1 5 10 15
<210>438
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>438
Val Glu Asp Lys Val Val Asp Pro Leu Pro Pro Tyr Leu Lys Gly
1 5 10 15
<210>439
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>439
Val Val Asp Pro Leu Pro Pro Tyr Leu Lys Gly Leu Asp Asp Leu
1 5 10 15
<210>440
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>440
Leu Pro Pro Tyr Leu Lys Gly Leu Asp Asp Leu Met Ser Gly Leu
1 5 10 15
<210>441
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>441
Leu Lys Gly Leu Asp Asp Leu Met Ser Gly Leu Gly Ala Ala Gly
1 5 10 15
<210>442
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>442
Asp Asp Leu Met Ser Gly Leu Gly Ala Ala Gly Lys Ala Val Gly
1 5 10 15
<210>443
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>443
Ser Gly Leu Gly Ala Ala Gly Lys Ala Val Gly Val Ala Ile Gly
1 5 10 15
<210>444
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>444
Ala Ala Gly Lys Ala Val Gly Val Ala Ile Gly Ala Val Gly Gly
1 5 10 15
<210>445
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>445
Ala Val Gly Val AlaIle Gly Ala Val Gly Gly Ala Val Ala Ser
1 5 10 15
<210>446
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>446
Ala Ile Gly Ala Val Gly Gly Ala Val Ala Ser Val Val Glu Gly
1 5 10 15
<210>447
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>447
Val Gly Gly Ala Val Ala Ser Val Val Glu Gly Val Ala Thr Phe
1 5 10 15
<210>448
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>448
Val Ala Ser Val Val Glu Gly Val Ala Thr Phe Leu Lys Asn Pro
1 5 10 15
<210>449
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>449
Val Glu Gly Val Ala Thr Phe Leu Lys Asn Pro Phe Gly Ala Phe
1 5 10 15
<210>450
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>450
Ala Thr Phe Leu Lys Asn Pro Phe Gly Ala Phe Thr Ile Ile Leu
1 5 10 15
<210>451
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>451
Lys Asn Pro Phe Gly Ala Phe Thr Ile Ile Leu Val Ala Ile Ala
1 5 10 15
<210>452
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>452
Gly Ala Phe Thr Ile Ile Leu Val Ala Ile Ala Val Val Ile Ile
1 5 10 15
<210>453
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>453
Ile Ile Leu Val Ala Ile Ala Val Val Ile Ile Thr Tyr Leu Ile
1 5 10 15
<210>454
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>454
Ala Ile Ala Val Val Ile Ile Thr Tyr Leu Ile Tyr Thr Arg Gln
1 5 10 15
<210>455
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>455
Val IleIle Thr Tyr Leu Ile Tyr Thr Arg Gln Arg Arg Leu Cys
1 5 10 15
<210>456
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>456
Tyr Leu Ile Tyr Thr Arg G1n Arg Arg Leu Cys Thr Gln Pro Leu
1 5 10 15
<210>457
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>457
Thr Arg Gln Arg Arg Leu Cys Thr Gln Pro Leu Gln Asn Leu Phe
1 5 10 15
<210>458
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>458
Arg Leu Cys Thr Gln Pro Leu Gln Asn Leu Phe Pro Tyr Leu Val
1 5 10 15
<210>459
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>459
Gln Pro Leu Gln Asn Leu Phe Pro Tyr Leu Val Ser Ala Asp Gly
1 5 10 15
<210>460
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>460
Asn Leu Phe Pro Tyr Leu Val Ser Ala Asp Gly Thr Thr Val Thr
1 5 10 15
<210>461
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>461
Tyr Leu Val Ser Ala Asp Gly Thr Thr Val Thr Ser G1y Ser Thr
1 5 10 15
<210>462
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>462
Ala Asp Gly Thr Thr Val Thr Ser Gly Ser Thr Lys Asp Thr Ser
1 5 10 15
<210>463
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>463
Thr Val Thr Ser Gly Ser Thr Lys Asp Thr Ser Leu Gln Ala Pro
1 5 10 15
<210>464
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>464
Gly Ser Thr Lys Asp Thr Ser Leu Gln Ala Pro Pro Ser Tyr Glu
1 5 10 15
<210>465
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>465
Asp Thr Ser Leu Gln Ala Pro Pro Ser Tyr Glu Glu Ser Val Tyr
1 5 10 15
<210>466
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>466
Gln Ala Pro Pro Ser Tyr Glu Glu Ser Val Tyr Asn Ser Gly Arg
1 5 10 15
<210>467
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>467
Ser Tyr Glu Glu Ser Val Tyr Asn Ser Gly Arg Lys Gly Pro Gly
1 5 10 15
<210>468
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>468
Ser Val Tyr Asn Ser Gly Arg Lys Gly Pro Gly Pro Pro Ser Ser
1 5 10 15
<210>469
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>469
Ser Gly Arg Lys Gly Pro Gly Pro Pro Ser Ser Asp Ala Ser Thr
1 5 10 15
<210>470
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>470
Gly Pro Gly Pro Pro Ser Ser Asp Ala Ser Thr Ala Ala Pro Pro
1 5 10 15
<210>471
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>471
Pro Ser Ser Asp Ala Ser Thr Ala Ala Pro Pro Tyr Thr Asn Glu
151015
<210>472
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>472
Ala Ser Thr Ala Ala Pro Pro Tyr Thr Asn Glu Gln Ala Tyr Gln
1 5 10 15
<210>473
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>473
Ala Pro Pro Tyr Thr Asn Glu Gln Ala Tyr Gln Met Leu Leu Ala
1 5 10 15
<210>474
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>474
Thr Asn Glu Gln Ala Tyr Gln Met Leu Leu Ala Leu Ala Arg Leu
1 5 10 15
<210>475
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>475
Ala Tyr Gln Met Leu Leu Ala Leu Ala Arg Leu Asp Ala Glu Gln
1 5 10 15
<210>476
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>476
Leu Leu Ala Leu Ala Arg Leu Asp Ala Glu Gln Arg Ala Gln Gln
1 5 10 15
<210>477
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>477
Ala Arg Leu Asp Ala Glu Gln Arg Ala Gln Gln Asn Gly Thr Asp
1 5 10 15
<210>478
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>478
Ala Glu Gln Arg Ala Gln Gln Asn Gly Thr Asp Ser Leu Asp Gly
1 5 10 15
<210>479
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>479
Ala Gln Gln Asn Gly Thr Asp Ser Leu Asp Gly Arg Thr Gly Thr
1 5 10 15
<210>480
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>480
Gly Thr Asp Ser Leu Asp Gly Arg Thr Gly Thr Gln Asp Lys Gly
1 5 10 15
<210>481
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>481
Leu Asp Gly Arg Thr Gly Thr Gln Asp Lys Gly Gln Lys Pro Asn
1 5 10 15
<210>482
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>482
Thr Gly Thr Gln Asp Lys Gly Gln Lys Pro Asn Leu Leu Asp Arg
1 5 10 15
<210>483
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>483
Asp Lys Gly Gln Lys Pro Asn Leu Leu Asp Arg Leu Arg His Arg
1 5 10 15
<210>484
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>484
Lys Pro Asn Leu Leu Asp Arg Leu Arg His Arg Lys Asn Gly Tyr
1 5 10 15
<210>485
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>485
Leu Asp Arg Leu Arg His Arg Lys Asn Gly Tyr Arg His Leu Lys
1 5 10 15
<210>486
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>486
Arg His Arg Lys Asn Gly Tyr Arg His Leu Lys Asp Ser Asp Glu
1 5 10 15
<210>487
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>487
Asn Gly Tyr Arg His Leu Lys Asp Ser Asp Glu Glu Glu Asn Val
1 5 10 15
<210>488
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>488
Met Asp Arg Lys Thr Arg Leu Ser Glu Pro Pro Thr Leu Ala Leu
1 5 10 15
<210>489
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>489
Thr Arg Leu Ser Glu Pro Pro Thr Leu Ala Leu Arg Leu Lys Pro
1 5 10 15
<210>490
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>490
Glu Pro Pro Thr Leu Ala Leu Arg Leu Lys Pro Tyr Lys Thr Ala
1 5 10 15
<210>491
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>491
Leu Ala Leu Arg Leu Lys Pro Tyr Lys Thr Ala Ile Gln Gln Leu
1 5 10 15
<210>492
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>492
Leu Lys Pro Tyr Lys Thr Ala Ile Gln Gln Leu Arg Ser Val Ile
1 5 10 15
<210>493
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>493
Lys Thr Ala Ile Gln Gln Leu Arg Ser Val Ile Arg Ala Leu Lys
1 5 10 15
<210>494
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>494
Gln Gln Leu Arg Ser Val Ile Arg Ala Leu Lys Glu Asn Thr Thr
1 5 10 15
<210>495
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>495
Ser Val Ile Arg Ala Leu Lys Glu Asn Thr Thr Val Thr Phe Leu
1 5 10 15
<210>496
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>496
Ala Leu Lys Glu Asn Thr Thr Val Thr Phe Leu Pro Thr Pro Ser
1 5 10 15
<210>497
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>497
Asn Thr Thr Val Thr Phe Leu Pro Thr Pro Ser Leu Ile Leu Gln
1 5 10 15
<210>498
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>498
Thr Phe Leu Pro Thr Pro Ser Leu Ile Leu Gln Thr Val Arg Ser
1 5 10 15
<210>499
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>499
Thr Pro Ser Leu Ile Leu Gln Thr Val Arg Ser His Cys Val Ser
1 5 10 15
<210>500
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>500
Ile Leu Gln Thr Val Arg Ser His Cys Val Ser Lys Ile Thr Phe
1 5 10 15
<210>501
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>501
Val Arg Ser His Cys Val Ser Lys Ile Thr Phe Asn Ser Ser Cys
1 5 10 15
<210>502
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>502
Cys Val Ser Lys Ile Thr Phe Asn Ser Ser Cys Leu Tyr Ile Thr
1 5 10 15
<210>503
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>503
Ile Thr Phe Asn Ser Ser Cys Leu Tyr Ile Thr Asp Lys Ser Phe
1 5 10 15
<210>504
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>504
Ser Ser Cys Leu Tyr Ile Thr Asp Lys Ser Phe Gln Pro Lys Thr
1 5 10 15
<210>505
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>505
Tyr Ile Thr Asp Lys Ser Phe Gln Pro Lys Thr Ile Asn Asn Ser
1 5 10 15
<210>506
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>506
Lys Ser Phe Gln Pro Lys Thr Ile Asn Asn Ser Thr Pro Leu Leu
1 5 10 15
<210>507
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>507
Pro Lys Thr Ile Asn Asn Ser Thr Pro Leu Leu Gly Asn Phe Met
1 5 10 15
<210>508
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>508
Asn Asn Ser Thr Pro Leu Leu Gly Asn Phe Met Tyr Leu Thr Ser
1 5 10 15
<210>509
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>509
Pro Leu Leu Gly Asn Phe Met Tyr Leu Thr Ser Ser Lys Asp Leu
1 5 10 15
<210>510
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>510
Asn Phe Met Tyr Leu Thr Ser Ser Lys Asp Leu Thr Lys Phe Tyr
1 5 10 15
<210>511
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>511
Leu Thr Ser Ser Lys Asp Leu Thr Lys Phe Tyr Val Gln Asp Ile
1 5 10 15
<210>512
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>512
Lys Asp Leu Thr Lys Phe Tyr Val Gln Asp Ile Ser Asp Leu Ser
1 5 10 15
<210>513
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>513
Lys Phe Tyr Val Gln Asp Ile Ser Asp Leu Ser Ala Lys Ile Ser
1 5 10 15
<210>514
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>514
Gln Asp Ile Ser Asp Leu Ser Ala Lys Ile Ser Met Cys Ala Pro
1 5 10 15
<210>515
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>515
Asp Leu Ser Ala Lys Ile Ser Met Cys Ala Pro Asp Phe Asn Met
1 5 10 15
<210>516
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>516
Lys Ile Ser Met Cys Ala Pro Asp Phe Asn Met Glu Phe Ser Ser
1 5 10 15
<210>517
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>517
Cys Ala Pro Asp Phe Asn Met Glu Phe Ser Ser Ala Cys Val His
1 5 10 15
<210>518
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>518
Phe Asn Met Glu Phe Ser Ser Ala Cys Val His Gly Gln Asp Ile
1 5 10 15
<210>519
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>519
Phe Ser Ser Ala Cys Val His Gly Gln Asp Ile Val Arg Glu Ser
1 5 10 15
<210>520
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>520
Cys Val His Gly Gln Asp Ile Val Arg Glu Ser Glu Asn Ser Ala
1 5 10 15
<210>521
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>521
Gln Asp Ile Val Arg Glu Ser Glu Asn Ser Ala Val His Val Asp
1 5 10 15
<210>522
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>522
Arg Glu Ser Glu Asn Ser Ala Val His Val Asp Leu Asp Phe Gly
1 5 10 15
<210>523
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>523
Asn Ser Ala Val His Val Asp Leu Asp Phe Gly Val Val Ala Asp
1 5 10 15
<210>524
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>524
His Val Asp Leu Asp Phe Gly Val Val Ala Asp Leu Leu Lys Trp
1 5 10 15
<210>525
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>525
Asp Phe Gly Val Val Ala Asp Leu Leu Lys Trp Ile Gly Pro His
1 5 10 15
<210>526
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>526
Val Ala Asp Leu Leu Lys Trp Ile Gly Pro His Thr Arg Val Lys
1 5 10 15
<210>527
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>527
Leu Lys Trp Ile Gly Pro His Thr Arg Val Lys Arg Asn Val Lys
1 5 10 15
<210>528
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>528
Gly Pro His Thr Arg Val Lys Arg Asn Val Lys Lys Ala Pro Cys
1 5 10 15
<210>529
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>529
Arg Val Lys Arg Asn Val Lys Lys Ala Pro Cys Pro Thr Gly Thr
1 5 10 15
<210>530
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>530
Asn Val Lys Lys Ala Pro Cys Pro Thr Gly Thr Val Gln Ile Leu
1 5 10 15
<210>531
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>531
Ala Pro Cys Pro Thr Gly Thr Val Gln Ile Leu Val His Ala Gly
1 5 10 15
<210>532
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>532
Thr Gly Thr Val Gln Ile Leu Val His Ala Gly Pro Pro Ala Ile
1 5 10 15
<210>533
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>533
Gln Ile Leu Val His Ala Gly Pro Pro Ala Ile Lys Phe Ile Leu
1 5 10 15
<210>534
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>534
His Ala Gly Pro Pro Ala Ile Lys Phe Ile Leu Thr Asn Gly Ser
1 5 10 15
<210>535
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>535
Pro Ala Ile Lys Phe Ile Leu Thr Asn Gly Ser Glu Leu Glu Phe
1 5 10 15
<210>536
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>536
Phe Ile Leu Thr Asn Gly Ser Glu Leu Glu Phe Thr Ala Asn Asn
1 5 10 15
<210>537
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>537
Asn Gly Ser Glu Leu Glu Phe Thr Ala Asn Asn Arg Val Ser Phe
1 5 10 15
<210>538
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>538
Leu Glu Phe Thr Ala Asn Asn Arg Val Ser Phe His Gly Val Lys
1 5 10 15
<210>539
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>539
Ala Asn Asn Arg Val Ser Phe His Gly Val Lys Asn Met Arg Ile
1 5 10 15
<210>540
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>540
Val Ser Phe His Gly Val Lys Asn Met Arg Ile Asn Val Gln Leu
1 5 10 15
<210>541
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>541
Gly Val Lys Asn Met Arg Ile Asn Val Gln Leu Lys Asn Phe Tyr
1 5 10 15
<210>542
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>542
Met Arg Ile Asn Val Gln Leu Lys Asn Phe Tyr Gln Thr Leu Leu
1 5 10 15
<210>543
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>543
Val Gln Leu Lys Asn Phe Tyr Gln Thr Leu Leu Asn Cys Ala Val
1 5 10 15
<210>544
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>544
Asn Phe Tyr Gln Thr Leu Leu Asn Cys Ala Val Thr Lys Leu Pro
1 5 10 15
<210>545
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>545
Thr Leu Leu Asn Cys Ala Val Thr Lys Leu Pro Cys Thr Leu Arg
1 5 10 15
<210>546
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>546
Cys Ala Val Thr Lys Leu Pro Cys Thr Leu Arg Ile Val Thr Glu
1 5 10 15
<210>547
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>547
Lys Leu Pro Cys Thr Leu Arg Ile Val Thr Glu His Asp Thr Leu
1 5 10 15
<210>548
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>548
Thr Leu ArgIle Val Thr Glu His Asp Thr Leu Leu Tyr Val Ala
1 5 10 15
<210>549
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>549
Val Thr Glu His Asp Thr Leu Leu Tyr Val Ala Ser Arg Asn Gly
1 5 10 15
<210>550
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>550
Asp Thr Leu Leu Tyr Val Ala Ser Arg Asn Gly Leu Phe Ala Val
1 5 10 15
<210>551
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>551
Tyr Val Ala Ser Arg Asn Gly Leu Phe Ala Val Glu Asn Phe Leu
1 5 10 15
<210>552
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>552
Arg Asn Gly Leu Phe Ala Val Glu Asn Phe Leu Thr Glu Glu Pro
1 5 10 15
<210>553
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>553
Phe Ala Val Glu Asn Phe Leu Thr Glu Glu Pro Phe Arg Arg Gly
1 5 10 15
<210>554
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>554
Asn Phe Leu Thr Glu Glu Pro Phe Arg Arg Gly Asp Pro Phe Asp
1 5 10 15
<210>555
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>555
Glu Glu Pro Phe Arg Arg Gly Asp Pro Phe Asp Lys Asn Tyr Val
1 5 10 15
<210>556
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>556
Arg Arg Gly Asp Pro Phe Asp Lys Asn Tyr Val Gly Asn Ser Gly
1 5 10 15
<210>557
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>557
Pro Phe Asp Lys Asn Tyr Val Gly Asn Ser Gly Lys Ser Arg Gly
1 5 10 15
<210>558
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>558
Asn Tyr Val Gly Asn Ser Gly Lys Ser Arg Gly Gly Gly Gly Gly
1 5 10 15
<210>559
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>559
Asn Ser Gly Lys Ser Arg Gly Gly Gly Gly Gly Gly Gly Ser Leu
1 5 10 15
<210>560
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>560
Ser Arg Gly Gly Gly Gly Gly Gly Gly Ser Leu Ser Ser Leu Ala
1 5 10 15
<210>561
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>561
Gly Gly Gly Gly Gly Ser Leu Ser Ser Leu Ala Asn Ala Gly Gly
1 5 10 15
<210>562
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>562
Gly Ser Leu Ser Ser Leu Ala Asn Ala Gly Gly Leu His Asp Asp
1 5 10 15
<210>563
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>563
Ser Leu Ala Asn Ala Gly Gly Leu His Asp Asp Gly Pro Gly Leu
1 5 10 15
<210>564
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>564
Ala Gly Gly Leu His Asp Asp Gly Pro Gly Leu Asp Asn Asp Leu
1 5 10 15
<210>565
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>565
His Asp Asp Gly Pro Gly Leu Asp Asn Asp Leu Met Asn Glu Pro
1 5 10 15
<210>566
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>566
Pro Gly Leu Asp Asn Asp Leu Met Asn Glu Pro Met Gly Leu Gly
1 5 10 15
<210>567
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>567
Asn Asp Leu Met Asn Glu Pro Met Gly Leu Gly Gly Leu Gly Gly
1 5 10 15
<210>568
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>568
Asn Glu Pro Met Gly Leu Gly Gly Leu Gly Gly Gly Gly Gly Gly
1 5 10 15
<210>569
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>569
Gly Leu Gly Gly Leu Gly Gly Gly Gly Gly Gly Gly Gly Lys Lys
1 5 10 15
<210>570
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>570
Leu Gly Gly Gly Gly Gly Gly Gly Gly Lys Lys His Asp Arg Gly
1 5 10 15
<210>571
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>571
Gly Gly Gly Gly Gly Lys Lys His Asp Arg Gly Gly Gly Gly Gly
1 5 10 15
<210>572
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>572
Gly Lys Lys His Asp Arg Gly Gly Gly Gly Gly Ser Gly Thr Arg
1 5 10 15
<210>573
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>573
Asp Arg Gly Gly Gly Gly Gly Ser Gly Thr Arg Lys Met Ser Ser
1 5 10 15
<210>574
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>574
Gly Gly Gly Ser Gly Thr Arg Lys Met Ser Ser Gly Gly Gly Gly
1 5 10 15
<210>575
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>575
Gly Thr Arg Lys Met Ser Ser Gly Gly Gly Gly Gly Asp His Asp
1 5 10 15
<210>576
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>576
Met Ser Ser Gly Gly Gly Gly Gly Asp His Asp His Gly Leu Ser
1 5 10 15
<210>577
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>577
Gly Gly Gly Gly Asp His Asp His Gly Leu Ser Ser Lys Glu Lys
1 5 10 15
<210>578
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>578
Asp His Asp His Gly Leu Ser Ser Lys Glu Lys Tyr Glu Gln His
1 5 10 15
<210>579
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>579
Gly Leu Ser Ser Lys Glu Lys Tyr Glu Gln His Lys Ile Thr Ser
1 5 10 15
<210>580
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>580
Lys Glu Lys Tyr Glu Gln His Lys Ile Thr Ser Tyr Leu Thr Ser
1 5 10 15
<210>581
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>581
Glu Gln His Lys Ile Thr Ser Tyr Leu Thr Ser Lys Gly Gly Ser
1 5 10 15
<210>582
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>582
Ile Thr Ser Tyr Leu Thr Ser Lys Gly Gly Ser Gly Gly Gly Gly
1 5 10 15
<210>583
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>583
Leu Thr Ser Lys Gly Gly Ser Gly Gly Gly Gly Gly Gly Gly Gly
1 5 10 15
<210>584
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>584
Gly Gly Ser Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Leu Asp
1 5 10 15
<210>585
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>585
Gly Gly Gly Gly Gly Gly Gly Gly Gly Leu Asp Arg Asn Ser Gly
1 5 10 15
<210>586
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>586
Gly Gly Gly Gly Gly Leu Asp Arg Asn Ser Gly Asn Tyr Phe Asn
1 5 10 15
<210>587
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>587
Gly Leu Asp Arg Asn Ser Gly Asn Tyr Phe Asn Asp Ala Lys Glu
1 5 10 15
<210>588
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>588
Asn Ser Gly Asn Tyr Phe Asn Asp Ala Lys Glu Glu SerAsp Ser
1 5 10 15
<210>589
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>589
Tyr Phe Asn Asp A1a Lys Glu Glu Ser Asp Ser Glu Asp Ser Val
1 5 10 15
<210>590
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>590
Ala Lys Glu Glu Ser Asp Ser Glu Asp Ser Val Thr Phe Glu Phe
1 5 10 15
<210>591
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>591
Ser Asp Ser Glu Asp Ser Val Thr Phe Glu Phe Val Pro Asn Thr
1 5 10 15
<210>592
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>592
Asp Ser Val Thr Phe Glu Phe Val Pro Asn Thr Lys Lys Gln Lys
1 5 10 15
<210>593
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>593
Val Thr Phe Glu Phe Val Pro Asn Thr Lys Lys Gln Lys Cys Gly
1 5 10 15
<210>594
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>594
Met Ser Leu Gln PheIle Gly Leu Gln Arg Arg Asp Val Val Ala
1 5 10 15
<210>595
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>595
Phe Ile Gly Leu Gln Arg Arg Asp Val Val Ala Leu Val Asn Phe
1 5 10 15
<210>596
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>596
Gln Arg Arg Asp Val Val Ala Leu Val Asn Phe Leu Arg His Leu
1 5 10 15
<210>597
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>597
Val Val Ala Leu Val Asn Phe Leu Arg His Leu Thr Gln Lys Pro
1 5 10 15
<210>598
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>598
Val Asn Phe Leu Arg His Leu Thr Gln Lys Pro Asp Val Asp Leu
1 5 10 15
<210>599
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>599
Arg His Leu Thr Gln Lys Pro Asp Val Asp Leu Glu Ala His Pro
1 5 10 15
<210>600
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>600
Gln Lys Pro Asp Val Asp Leu Glu Ala His Pro Lys Ile Leu Lys
1 5 10 15
<210>601
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>601
Val Asp Leu Glu Ala His Pro Lys Ile Leu Lys Lys Cys Gly Glu
1 5 10 15
<210>602
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>602
Ala His Pro Lys Ile Leu Lys Lys Cys Gly Glu Lys Arg Leu His
1 5 10 15
<210>603
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>603
Ile Leu Lys Lys Cys Gly Glu Lys Arg Leu His Arg Arg Thr Val
1 5 10 15
<210>604
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>604
Cys Gly G1u Lys Arg Leu His Arg Arg Thr Val Leu Phe Asn Glu
1 5 10 15
<210>605
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>605
Arg Leu His Arg Arg Thr Val Leu Phe Asn Glu Leu Met Leu Trp
1 5 10 15
<210>606
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>606
Arg Thr Val Leu Phe Asn Glu Leu Met Leu Trp Leu Gly Tyr Tyr
1 5 10 15
<210>607
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>607
Phe Asn Glu Leu Met Leu Trp Leu Gly Tyr Tyr Arg Glu Leu Arg
1 5 10 15
<210>608
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>608
Met Leu Trp Leu Gly Tyr Tyr Arg Glu Leu Arg Phe His Asn Pro
1 5 10 15
<210>609
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>609
Gly Tyr Tyr Arg Glu Leu Arg Phe His Asn Pro Asp Leu Ser Ser
1 5 10 15
<210>610
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>610
Glu Leu Arg Phe His Asn Pro Asp Leu Ser Ser Val Leu Glu Glu
1 5 10 15
<210>611
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>611
His Asn Pro Asp Leu Ser Ser Val Leu Glu Glu Phe Glu Val Arg
1 5 10 15
<210>612
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>612
Leu Ser Ser Val Leu Glu Glu Phe Glu Val Arg Cys Ala Ala Val
1 5 10 15
<210>613
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>613
Leu Glu Glu Phe Glu Val Arg Cys Ala Ala Val Ala Arg Arg Gly
1 5 10 15
<210>614
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>614
Glu Val Arg Cys Ala Ala Val Ala Arg Arg Gly Tyr Thr Tyr Pro
1 5 10 15
<210>615
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>615
Ala Ala Val Ala Arg Arg Gly Tyr Thr Tyr Pro Phe Gly Asp Arg
1 5 10 15
<210>616
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>616
Arg Arg Gly Tyr Thr Tyr Pro Phe Gly Asp Arg Gly Lys Ala Arg
1 5 10 15
<210>617
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>617
Thr Tyr Pro Phe Gly Asp Arg Gly Lys Ala Arg Asp His Leu Ala
1 5 10 15
<210>618
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>618
Gly Asp Arg Gly Lys Ala Arg Asp His Leu Ala Val Leu Asp Arg
1 5 10 15
<210>619
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>619
Lys Ala Arg Asp His Leu Ala Val Leu Asp Arg Thr Glu Phe Asp
1 5 10 15
<210>620
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>620
His Leu Ala Val Leu Asp Arg Thr Glu Phe Asp Thr Asp Val Arg
1 5 10 15
<210>621
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>621
Leu Asp Arg Thr Glu Phe Asp Thr Asp Val Arg His Asp Ala Glu
1 5 10 15
<210>622
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>622
Glu Phe Asp Thr Asp Val Arg His Asp Ala Glu Ile Val Glu Arg
1 5 10 15
<210>623
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>623
Asp Val Arg His Asp Ala Glu Ile Val Glu Arg Ala Leu Val Ser
1 5 10 15
<210>624
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>624
Asp Ala Glu Ile Val Glu Arg Ala Leu Val Ser Ala Val Ile Leu
1 5 10 15
<210>625
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>625
Val Glu Arg Ala Leu Val Ser Ala Val Ile Leu Ala Lys Met Ser
1 5 10 15
<210>626
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>626
Leu Val Ser Ala Val Ile Leu Ala Lys Met Ser Val Arg Glu Thr
1 5 10 15
<210>627
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>627
Val Ile Leu Ala Lys Met Ser Val Arg Glu Thr Leu Val Thr Ala
1 5 10 15
<210>628
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>628
Lys Met Ser Val Arg Glu Thr Leu Val Thr Ala Ile Gly Gln Thr
1 5 10 15
<210>629
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>629
Arg Glu Thr Leu Val Thr Ala Ile Gly Gln Thr Glu Pro Ile Ala
1 5 10 15
<210>630
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>630
Val Thr Ala Ile Gly Gln Thr Glu ProIle Ala Phe Val His Leu
1 5 10 15
<210>631
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>631
Gly Gln Thr Glu Pro Ile Ala Phe Val His Leu Lys Asp Thr Glu
1 5 10 15
<210>632
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>632
Pro Ile Ala Phe Val His Leu Lys Asp Thr Glu Val Gln Arg Ile
1 5 10 15
<210>633
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>633
Val His Leu Lys Asp Thr Glu Val Gln Arg Ile Glu Glu Asn Leu
1 5 10 15
<210>634
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>634
Asp Thr Glu Val Gln Arg Ile Glu Glu Asn Leu Glu Gly Val Arg
1 5 10 15
<210>635
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>635
Gln Arg Ile Glu Glu Asn Leu Glu Gly Val Arg Arg Asn Met Phe
1 5 10 15
<210>636
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>636
Glu Asn Leu Glu Gly Val Arg Arg Asn Met Phe Cys Val Lys Pro
1 5 10 15
<210>637
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>637
Gly Val Arg Arg Asn Met Phe Cys Val Lys Pro Leu Asp Leu Asn
1 5 10 15
<210>638
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>638
Asn Met Phe Cys Val Lys Pro Leu Asp Leu Asn Leu Asp Arg His
1 5 10 15
<210>639
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>639
Val Lys Pro Leu Asp Leu Asn Leu Asp Arg His Ala Asn Thr Ala
1 5 10 15
<210>640
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>640
Asp Leu Asn Leu Asp Arg His Ala Asn Thr Ala Leu Val Asn Ala
1 5 10 15
<210>641
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>641
Asp Arg His Ala Asn Thr Ala Leu Val Asn Ala Val Asn Lys Leu
1 5 10 15
<210>642
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>642
Asn Thr Ala Leu Val Asn Ala Val Asn Lys Leu Val Tyr Thr Gly
1 5 10 15
<210>643
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>643
Val Asn Ala Val Asn Lys Leu Val Tyr Thr Gly Arg Leu Ile Met
1 5 10 15
<210>644
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>644
Asn Lys Leu Val Tyr Thr Gly Arg Leu Ile Met Asn Val Arg Arg
1 5 10 15
<210>645
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>645
Tyr Thr Gly Arg Leu Ile Met Asn Val Arg Arg Ser Trp Glu Glu
1 5 10 15
<210>646
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>646
Leu Ile Met Asn Val Arg Arg Ser Trp Glu Glu Leu Glu Arg Lys
1 5 10 15
<210>647
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>647
Val Arg Arg Ser Trp Glu Glu Leu Glu Arg Lys Cys Leu Ala Arg
1 5 10 15
<210>648
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>648
Trp Glu Glu Leu Glu Arg Lys Cys Leu Ala Arg Ile Gln Glu Arg
1 5 10 15
<210>649
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>649
Glu Arg Lys Cys Leu Ala Arg Ile Gln Glu Arg Cys Lys Leu Leu
1 5 10 15
<210>650
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>650
Leu Ala Arg Ile Gln Glu Arg Cys Lys Leu Leu Val Lys Glu Leu
1 5 10 15
<210>651
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>651
Gln Glu Arg Cys Lys Leu Leu Val Lys Glu Leu Arg Met Cys Leu
1 5 10 15
<210>652
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>652
Lys Leu Leu Val Lys Glu Leu Arg Met Cys Leu Ser Phe Asp Ser
1 5 10 15
<210>653
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>653
Lys Glu Leu Arg Met Cys Leu Ser Phe Asp Ser Asn Tyr Cys Arg
1 5 10 15
<210>654
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>654
Met Cys Leu Ser Phe Asp Ser Asn Tyr Cys Arg Asn Ile Leu Lys
1 5 10 15
<210>655
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>655
Phe Asp Ser Asn Tyr Cys Arg Asn Ile Leu Lys His Ala Val Glu
1 5 10 15
<210>656
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>656
Tyr Cys Arg Asn Ile Leu Lys His Ala Val Glu Asn Gly Asp Ser
1 5 10 15
<210>657
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>657
Ile Leu Lys His Ala Val Glu Asn Gly Asp Ser Ala Asp Thr Leu
1 5 10 15
<210>658
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>658
Ala Val Glu Asn Gly Asp Ser Ala Asp Thr Leu Leu Glu Leu Leu
1 5 10 15
<210>659
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>659
Gly Asp Ser Ala Asp Thr Leu Leu Glu Leu LeuIle Glu Asp Phe
1 5 10 15
<210>660
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>660
Asp Thr Leu Leu Glu Leu Leu Ile Glu Asp Phe Asp Ile Tyr Val
1 5 10 15
<210>661
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>661
Glu Leu LeuIle Glu Asp Phe Asp Ile Tyr Val Asp Ser Phe Pro
1 5 10 15
<210>662
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>662
Glu Asp Phe Asp Ile Tyr Val Asp Ser Phe Pro Gln Ser Ala His
1 5 10 15
<210>663
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>663
Ile Tyr Val Asp Ser Phe Pro Gln Ser Ala His Thr Phe Leu Gly
1 5 10 15
<210>664
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>664
Ser Phe Pro Gln Ser Ala His Thr Phe Leu Gly Ala Arg Pro Pro
1 5 10 15
<210>665
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>665
Ser Ala His Thr Phe Leu Gly Ala Arg Pro Pro Ser Leu Glu Phe
1 5 10 15
<210>666
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>666
Phe Leu Gly Ala Arg Pro Pro Ser Leu Glu Phe Asp Asp Asp Ala
1 5 10 15
<210>667
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>667
Arg Pro Pro Ser Leu Glu Phe Asp Asp Asp Ala Asn Leu Leu Ser
1 5 10 15
<210>668
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>668
Leu Glu Phe Asp Asp Asp Ala Asn Leu Leu Ser Leu Gly Gly Gly
1 5 10 15
<210>669
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>669
Asp Asp Ala Asn Leu Leu Ser Leu Gly Gly Gly Ser Ala Phe Ser
1 5 10 15
<210>670
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>670
Leu Leu Ser Leu Gly Gly Gly Ser Ala Phe Ser Ser Val Pro Lys
1 5 10 15
<210>671
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>671
Gly Gly Gly Ser Ala Phe Ser Ser Val Pro Lys Lys His Val Pro
1 5 10 15
<210>672
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>672
Ala Phe Ser Ser Val Pro Lys Lys His Val Pro Thr Gln Pro Leu
1 5 10 15
<210>673
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>673
Val Pro Lys Lys His Val Pro Thr Gln Pro Leu Asp Gly Trp Ser
1 5 10 15
<210>674
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>674
His Val Pro Thr Gln Pro Leu Asp Gly Trp Ser Trp Ile Ala Ser
1 5 10 15
<210>675
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>675
Gln Pro Leu Asp Gly Trp Ser Trp Ile Ala Ser Pro Trp Lys Gly
1 5 10 15
<210>676
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>676
Gly Trp Ser Trp Ile Ala Ser Pro Trp Lys Gly His Lys Pro Phe
1 5 10 15
<210>677
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>677
Ile Ala Ser Pro Trp Lys Gly His Lys Pro Phe Arg Phe Glu Ala
1 5 10 15
<210>678
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>678
Trp Lys Gly His Lys Pro Phe Arg Phe Glu Ala His Gly Ser Leu
1 5 10 15
<210>679
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>679
Lys Pro Phe Arg Phe Glu Ala His Gly Ser Leu Ala Pro Ala Ala
1 5 10 15
<210>680
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>680
Phe Glu Ala His Gly Ser Leu Ala Pro Ala Ala Asp Ala His Ala
1 5 10 15
<210>681
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>681
Gly Ser Leu Ala Pro Ala Ala Asp Ala His Ala Ala Arg Ser Ala
1 5 10 15
<210>682
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>682
Pro Ala Ala Asp Ala His Ala Ala Arg Ser Ala Ala Val Gly Tyr
1 5 10 15
<210>683
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>683
Ala His Ala Ala Arg Ser Ala Ala Val Gly Tyr Tyr Asp Glu Glu
1 5 10 15
<210>684
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>684
Arg Ser Ala Ala Val Gly Tyr Tyr Asp Glu Glu G1u Lys Arg Arg
1 5 10 15
<210>685
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>685
Val Gly Tyr Tyr Asp Glu Glu Glu Lys Arg Arg Glu Arg G1n Lys
1 5 10 15
<210>686
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>686
Asp Glu Glu Glu Lys Arg Arg Glu Arg Gln Lys Arg Val Asp Asp
1 5 10 15
<210>687
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>687
Lys Arg Arg Glu Arg Gln Lys Arg Val Asp Asp Glu Val Val Gln
1 5 10 15
<210>688
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>688
Arg Gln Lys Arg Val Asp Asp Glu Val Val Gln Arg Glu Lys Gln
1 5 10 15
<210>689
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>689
Val Asp Asp Glu Val Val Gln Arg Glu Lys Gln Gln Leu Lys Ala
1 5 10 15
<210>690
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>690
Val Val Gln Arg Glu Lys Gln Gln Leu Lys Ala Trp Glu Glu Arg
1 5 10 15
<210>691
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>691
Glu Lys Gln Gln Leu Lys Ala Trp Glu Glu Arg Gln Gln Asn Leu
1 5 10 15
<210>692
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>692
Leu Lys Ala Trp Glu Glu Arg Gln Gln Asn Leu Gln Gln Arg Gln
1 5 10 15
<210>693
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>693
Glu Glu Arg Gln Gln Asn Leu Gln Gln Arg Gln Gln Gln Pro Pro
1 5 10 15
<210>694
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>694
Gln Asn Leu Gln Gln Arg Gln Gln Gln Pro Pro Pro Pro Thr Arg
1 5 10 15
<210>695
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>695
Gln Arg Gln Gln Gln Pro Pro Pro Pro Thr Arg Lys Pro Gly Ala
1 5 10 15
<210>696
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>696
Gln Pro Pro Pro Pro Thr Arg Lys Pro Gly Ala Ser Arg Arg Leu
1 5 10 15
<210>697
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>697
Pro Thr Arg Lys Pro Gly Ala Ser Arg Arg Leu Phe Gly Ser Ser
1 5 10 15
<210>698
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>698
Pro Gly Ala Ser Arg Arg Leu Phe Gly Ser Ser Ala Asp Glu Asp
1 5 10 15
<210>699
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>699
Arg Arg Leu Phe Gly Ser Ser Ala Asp Glu Asp Asp Asp Asp Asp
1 5 10 15
<210>700
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>700
Gly Ser Ser Ala Asp Glu Asp Asp Asp Asp Asp Asp Asp Glu Lys
1 5 10 15
<210>701
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>701
Asp Glu Asp Asp Asp Asp Asp Asp Asp Glu Lys Asn Ile Phe Thr
1 5 10 15
<210>702
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>702
Asp Asp Asp Asp Asp Glu Lys Asn Ile Phe Thr Pro Ile Lys Lys
1 5 10 15
<210>703
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegal ovirus
<400>703
Asp Glu Lys Asn Ile Phe Thr Pro Ile Lys Lys Pro Gly Thr Ser
1 5 10 15
<210>704
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>704
Ile Phe Thr Pro Ile Lys Lys Pro Gly Thr Ser Gly Lys Gly Ala
1 5 10 15
<210>705
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>705
Ile Lys Lys Pro Gly Thr Ser Gly Lys Gly Ala Ala Ser Gly Asn
1 5 10 15
<210>706
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>706
Gly Thr Ser Gly Lys Gly Ala Ala Ser Gly Asn Gly Val Ser Ser
1 5 10 15
<210>707
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>707
Lys Gly Ala Ala Ser Gly Asn Gly Val Ser Ser Ile Phe Ser Gly
1 5 10 15
<210>708
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>708
Ser Gly Asn Gly Val Ser Ser Ile Phe Ser Gly Met Leu Ser Ser
1 5 10 15
<210>709
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>709
Val Ser Ser Ile Phe Ser Gly Met Leu Ser Ser Gly Ser Gln Lys
1 5 10 15
<210>710
<211>15
<212>PRT
<213>Artificialn <220>
<223>Human cytomegalovirus
<400>710
Phe Ser Gly Met Leu Ser Ser Gly Ser Gln Lys Pro Thr Ser Gly
1 5 10 15
<210>711
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>711
Leu Ser Ser Gly Ser Gln Lys Pro Thr Ser Gly Pro Leu Asn Ile
1 5 10 15
<210>712
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>712
Ser Gln Lys Pro Thr Ser Gly Pro Leu Asn Ile Pro Gln Gln Gln
1 5 10 15
<210>713
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>713
Thr Ser Gly Pro Leu Asn Ile Pro Gln Gln Gln Gln Arg His Ala
1 5 10 15
<210>714
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>714
Leu Asn Ile Pro Gln Gln Gln Gln Arg His Ala Ala Phe Ser Leu
1 5 10 15
<210>715
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>715
Gln Gln Gln Gln Arg His Ala Ala Phe Ser Leu Val Ser Pro Gln
1 5 10 15
<210>716
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>716
Arg His Ala Ala Phe Ser Leu Val Ser Pro Gln Val Thr Lys Ala
1 5 10 15
<210>717
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>717
Phe Ser Leu Val Ser Pro Gln Val Thr Lys Ala Ser Pro Gly Arg
1 5 10 15
<210>718
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>718
Ser Pro Gln Val Thr Lys Ala Ser Pro Gly Arg Val Arg Arg Asp
1 5 10 15
<210>719
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>719
Thr Lys Ala Ser Pro Gly Arg Val Arg Arg Asp Ser Ala Trp Asp
1 5 10 15
<210>720
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>720
Pro Gly Arg Val Arg Arg Asp Ser Ala Trp Asp Val Arg Pro Leu
1 5 10 15
<210>721
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovi rus
<400>721
Arg Arg Asp Ser Ala Trp Asp Val Arg Pro Leu Thr Glu Thr Arg
1 5 10 15
<210>722
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>722
Ala Trp Asp Val Arg Pro Leu Thr Glu Thr Arg Gly Asp Leu Phe
1 5 10 15
<210>723
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>723
Arg Pro Leu Thr Glu Thr Arg Gly Asp Leu Phe Ser Gly Asp Glu
1 5 10 15
<210>724
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>724
Glu Thr Arg Gly Asp Leu Phe Ser Gly Asp Glu Asp Ser Asp Ser
1 5 10 15
<210>725
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>725
Asp Leu Phe Ser Gly Asp Glu Asp Ser Asp Ser Ser Asp Gly Tyr
1 5 10 15
<210>726
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>726
Gly Asp Glu Asp Ser Asp Ser Ser Asp Gly Tyr Pro Pro Asn Arg
1 5 10 15
<210>727
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>727
Ser Asp Ser Ser Asp Gly Tyr Pro Pro Asn Arg Gln Asp Pro Arg
1 5 10 15
<210>728
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>728
Asp Gly Tyr Pro Pro Asn Arg Gln Asp Pro Arg Phe Thr Asp Thr
1 5 10 15
<210>729
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>729
Pro Asn Arg Gln Asp Pro Arg Phe Thr Asp Thr Pro Val Asp Ile
1 5 10 15
<210>730
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>730
Asp Pro Arg Phe Thr Asp Thr Pro Val Asp Ile Thr Asp Thr Glu
1 5 10 15
<210>731
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>731
Thr Asp Thr Pro Val Asp Ile Thr Asp Thr Glu Thr Ser Ala Lys
1 5 10 15
<2L0>732
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>732
Val Asp Ile Thr Asp Thr Glu Thr Ser Ala Lys Pro Pro Val Thr
1 5 10 15
<210>733
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>733
Asp Thr Glu Thr Ser Ala Lys Pro Pro Val Thr Thr Ala Tyr Lys
1 5 10 15
<210>734
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>734
Ser Ala Lys Pro Pro Val Thr Thr Ala Tyr Lys Phe Glu Gln Pro
1 5 10 15
<210>735
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>735
Pro Val Thr Thr Ala Tyr Lys Phe Glu Gln Pro Thr Leu Thr Phe
1 5 10 15
<210>736
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>736
Ala Tyr Lys Phe Glu Gln Pro Thr Leu Thr Phe Gly Ala Gly Val
1 5 10 15
<210>737
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>737
Glu Gln Pro Thr Leu Thr Phe Gly Ala Gly Val Asn Val Pro Ala
1 5 10 15
<210>738
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>738
Leu Thr Phe Gly Ala Gly Val Asn Val Pro Ala Gly Ala Gly Ala
1 5 10 15
<210>739
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>739
Ala Gly Val Asn Val Pro Ala Gly Ala Gly Ala Ala Ile Leu Thr
1 5 10 15
<210>740
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>740
Val Pro Ala Gly Ala Gly Ala Ala Ile Leu Thr Pro Thr Pro Val
1 5 10 15
<210>741
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>741
Ala Gly Ala Ala Ile Leu Thr Pro Thr Pro Val Asn Pro Ser Thr
1 5 10 15
<210>742
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>742
Ile Leu Thr Pro Thr Pro Val Asn Pro Ser Thr Ala Pro Ala Pro
1 5 10 15
<210>743
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>743
Thr Pro Val Asn Pro Ser Thr Ala Pro Ala Pro Ala Pro Thr Pro
1 5 10 15
<210>744
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>744
Pro Ser Thr Ala Pro Ala Pro Ala Pro Thr Pro Thr Phe Ala Gly
1 5 10 15
<210>745
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>745
Pro Ala Pro Ala Pro Thr Pro Thr Phe Ala Gly Thr Gln Thr Pro
1 5 10 15
<210>746
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>746
Pro Thr Pro Thr Phe Ala Gly Thr Gln Thr Pro Val Asn Gly Asn
1 5 10 15
<210>747
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>747
Phe Ala Gly Thr Gln Thr Pro Val Asn Gly Asn Ser Pro Trp Ala
1 5 10 15
<210>748
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>748
Gln Thr Pro Val Asn Gly Asn Ser Pro Trp Ala Pro Thr Ala Pro
1 5 10 15
<210>749
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>749
Asn Gly Asn Ser Pro Trp Ala Pro Thr Ala Pro Leu Pro Gly Asp
1 5 10 15
<210>750
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>750
Pro Trp Ala Pro Thr Ala Pro Leu Pro Gly Asp Met Asn Pro Ala
1 5 10 15
<210>751
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>751
Thr Ala Pro Leu Pro Gly Asp Met Asn Pro Ala Asn Trp Pro Arg
1 5 10 15
<210>752
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>752
Pro Gly Asp Met Asn Pro Ala Asn Trp Pro Arg Glu Arg Ala Trp
1 5 10 15
<210>753
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>753
Asn Pro Ala Asn Trp Pro Arg Glu Arg Ala Trp Ala Leu Lys Asn
1 5 10 15
<210>754
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>754
Trp Pro Arg Glu Arg Ala Trp Ala Leu Lys Asn Pro His Leu Ala
1 5 10 15
<210>755
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegal ovirus
<400>755
Arg Ala Trp Ala Leu Lys Asn Pro His Leu Ala Tyr Asn Pro Phe
1 5 10 15
<210>756
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>756
Leu Lys Asn Pro His Leu Ala Tyr Asn Pro Phe Arg Met Pro Thr
1 5 10 15
<210>757
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>757
His Leu Ala Tyr Asn Pro Phe Arg Met Pro Thr Thr Ser Thr Thr
1 5 10 15
<210>758
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>758
Asn Pro Phe Arg Met Pro Thr Thr Ser Thr Thr Ser Gln Asn Asn
1 5 10 15
<210>759
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>759
Met Pro Thr Thr Ser Thr Thr Ser Gln Asn Asn Val Ser Thr Thr
1 5 10 15
<210>760
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>760
Ser Thr Thr Ser Gln Asn Asn Val Ser Thr Thr Pro Arg Arg Pro
1 5 10 15
<210>761
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>761
Gln Asn Asn Val Ser Thr Thr Pro Arg Arg Pro Ser Thr Pro Arg
1 5 10 15
<210>762
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>762
Ser Thr Thr Pro Arg Arg Pro Ser Thr Pro Arg Ala Ala Val Thr
1 5 10 15
<210>763
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>763
Arg Arg Pro Ser Thr Pro Arg Ala Ala Val Thr Gln Thr Ala Ser
1 5 10 15
<210>764
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>764
Thr Pro Arg Ala Ala Val Thr Gln Thr Ala Ser Gln Asn Ala Ala
1 5 10 15
<210>765
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>765
Ala Val Thr Gln Thr Ala Ser Gln Asn Ala Ala Asp Glu Val Trp
1 5 10 15
<210>766
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>766
Thr Ala Ser Gln Asn Ala Ala Asp Glu Val Trp Ala Leu Arg Asp
1 5 10 15
<210>767
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>767
Asn Ala Ala Asp Glu Val Trp Ala Leu Arg Asp Gln Thr Ala Glu
1 5 10 15
<210>768
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>768
Glu Val Trp Ala Leu Arg Asp Gln Thr Ala Glu Ser Pro Val Glu
1 5 10 15
<210>769
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>769
Leu Arg Asp Gln Thr Ala Glu Ser Pro Val Glu Asp Ser Glu Glu
1 5 10 15
<210>770
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>770
Thr Ala Glu Ser Pro Val Glu Asp Ser Glu Glu Glu Asp Asp Asp
1 5 10 15
<210>771
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>771
Pro Val Glu Asp Ser Glu Glu Glu Asp Asp Asp Ser Ser Asp Thr
1 5 10 15
<210>772
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>772
Ser Glu Glu Glu Asp Asp Asp Ser Ser Asp Thr Gly Ser Val Val
1 5 10 15
<210>773
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>773
Asp Asp Asp Ser Ser Asp Thr Gly Ser Val Val Ser Leu Gly His
1 5 10 15
<210>774
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>774
Ser Asp Thr Gly Ser Val Val Ser Leu Gly His Thr Thr Pro Ser
1 5 10 15
<210>775
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>775
Ser Val Val Ser Leu Gly His Thr Thr Pro Ser Ser Asp Tyr Asn
1 5 10 15
<210>776
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>776
Leu Gly His Thr Thr Pro Ser Ser Asp Tyr Asn Asp Val Ile Ser
1 5 10 15
<210>777
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>777
Thr Pro Ser Ser Asp Tyr Asn Asp Val Ile Ser Pro Pro Ser Gln
1 5 10 15
<210>778
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>778
Asp Tyr Asn Asp Val Ile Ser Pro Pro Ser Gln Thr Pro Glu Gln
1 5 10 15
<210>779
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>779
Val Ile Ser Pro Pro Ser Gln Thr Pro Glu Gln Ser Thr Pro Ser
1 5 10 15
<210>780
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>780
Pro Ser Gln Thr Pro Glu Gln Ser Thr Pro Ser Arg Ile Arg Lys
1 5 10 15
<210>781
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>781
Pro Glu Gln Ser Thr Pro Ser Arg Ile Arg Lys Ala Lys Leu Ser
1 5 10 15
<210>782
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>782
Thr Pro Ser Arg Ile Arg Lys Ala Lys Leu Ser Ser Pro Met Thr
1 5 10 15
<210>783
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>783
Ile Arg Lys Ala Lys Leu Ser Ser Pro Met Thr Thr Thr Ser Thr
1 5 10 15
<210>784
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>784
Lys Leu Ser Ser Pro Met Thr Thr Thr Ser Thr Ser Gln Lys Pro
1 5 10 15
<210>785
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>785
Pro Met Thr Thr Thr Ser Thr Ser Gln Lys Pro Val Leu Gly Lys
1 5 10 15
<210>786
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>786
Thr Ser Thr Ser Gln Lys Pro Val Leu Gly Lys Arg Val Ala Thr
1 5 10 15
<210>787
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>787
Gln Lys Pro Val Leu Gly Lys Arg Val Ala Thr Pro His Ala Ser
1 5 10 15
<210>788
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>788
Leu Gly Lys Arg Val Ala Thr Pro His Ala Ser Ala Arg Ala Gln
1 5 10 15
<210>789
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>789
Val Ala Thr Pro His Ala Ser Ala Arg Ala Gln Thr Val Thr Ser
1 5 10 15
<210>790
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>790
His Ala Ser Ala Arg Ala Gln Thr Val Thr Ser Thr Pro Val Gln
1 5 10 15
<210>791
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>791
Arg Ala Gln Thr Val Thr Ser Thr Pro Val Gln Gly Arg Val Glu
1 5 10 15
<210>792
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>792
Val Thr Ser Thr Pro Val Gln Gly Arg Val Glu Lys Gln Val Ser
1 5 10 15
<210>793
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>793
Pro Val Gln Gly Arg Val Glu Lys Gln Val Ser Gly Thr Pro Ser
1 5 10 15
<210>794
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>794
Arg Val Glu Lys Gln Val Ser Gly Thr Pro Ser Thr Val Pro Ala
1 5 10 15
<210>795
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>795
Gln Val Ser Gly Thr Pro Ser Thr Val Pro Ala Thr Leu Leu Gln
1 5 10 15
<210>796
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>796
Thr Pro Ser Thr Val Pro Ala Thr Leu Leu Gln Pro Gln Pro Ala
1 5 10 15
<210>797
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>797
Val Pro Ala Thr Leu Leu Gln Pro Gln Pro Ala Ser Ser Lys Thr
1 5 10 15
<210>798
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>798
Leu Leu Gln Pro Gln Pro Ala Ser Ser Lys Thr Thr Ser Ser Arg
1 5 10 15
<210>799
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>799
Gln Pro Ala Ser Ser Lys Thr Thr Ser Ser Arg Asn Val Thr Ser
1 5 10 15
<210>800
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>800
Ser Lys Thr Thr Ser Ser Arg Asn Val Thr Ser Gly Ala Arg Thr
1 5 10 15
<210>801
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>801
Ser Ser Arg Asn Val Thr Ser Gly Ala Arg Thr Ser Ser Ala Ser
1 5 10 15
<210>802
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>802
Val Thr Ser Gly Ala Arg Thr Ser Ser Ala Ser Ala Arg Gln Pro
1 5 10 15
<210>803
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>803
Ala Arg Thr Ser Ser Ala Ser Ala Arg Gln Pro Ser Ala Ser Ala
1 5 10 15
<210>804
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>804
Ser Ala Ser Ala Arg Gln Pro Ser Ala Ser Ala Ser Val Leu Ser
1 5 10 15
<210>805
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>805
Arg Gln Pro Ser Ala Ser Ala Ser Val Leu Ser Pro Thr Glu Asp
1 5 10 15
<210>806
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>806
Ala Ser Ala Ser Val Leu Ser Pro Thr Glu Asp Asp Val Val Ser
1 5 10 15
<210>807
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>807
Val Leu Ser Pro Thr Glu Asp Asp Val Val Ser Pro Val Thr Ser
1 5 10 15
<210>808
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>808
Thr Glu Asp Asp Val Val Ser Pro Val Thr Ser Pro Leu Ser Met
1 5 10 15
<210>809
<211>15
<212>PRT
<213>Art ificial
<220>
<223>Human cytomegalovirus
<400>809
Val Val Ser Pro Val Thr Ser Pro Leu Ser Met Leu Ser Ser Ala
1 5 10 15
<210>810
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>810
Val Thr Ser Pro Leu Ser Met Leu Ser Ser Ala Ser Pro Ser Pro
1 5 10 15
<210>811
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>811
Leu Ser Met Leu Ser Ser Ala Ser Pro Ser Pro Ala Lys Ser Ala
1 5 10 15
<210>812
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>812
Ser Ser Ala Ser Pro Ser Pro Ala Lys Ser Ala Pro Pro Ser Pro
1 5 10 15
<210>813
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>813
Pro Ser Pro Ala Lys Ser Ala Pro Pro Ser Pro Val Lys Gly Arg
1 5 10 15
<210>814
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>814
Lys Ser Ala Pro Pro Ser Pro Val Lys Gly Arg Gly Ser Arg Val
1 5 10 15
<210>815
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>815
Pro Ser Pro Val Lys Gly Arg Gly Ser Arg Val Gly Val Pro Ser
1 5 10 15
<210>816
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>816
Lys Gly Arg Gly Ser Arg Val Gly Val Pro Ser Leu Lys Pro Thr
1 5 10 15
<210>817
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>817
Ser Arg Val Gly Val Pro Ser Leu Lys Pro Thr Leu Gly Gly Lys
1 5 10 15
<210>818
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>818
Val Pro Ser Leu Lys Pro Thr Leu Gly Gly Lys Ala Val Val Gly
1 5 10 15
<210>819
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>819
Lys Pro Thr Leu Gly Gly Lys Ala Val Val Gly Arg Pro Pro Ser
1 5 10 15
<210>820
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>820
Gly Gly Lys Ala Val Val Gly Arg Pro Pro Ser Val Pro Val Ser
1 5 10 15
<210>821
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>821
Val Val Gly Arg Pro Pro Ser Val Pro Val Ser Gly Ser Ala Pro
1 5 10 15
<210>822
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>822
Pro Pro Ser Val Pro Val Ser Gly Ser Ala Pro Gly Arg Leu Ser
1 5 10 15
<210>823
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>823
Pro Val Ser Gly Ser Ala Pro Gly Arg Leu Ser Gly Thr Ser Arg
1 5 10 15
<210>824
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>824
Ser Ala Pro Gly Arg Leu Ser Gly Thr Ser Arg Ala Ala Ser Thr
1 5 10 15
<210>825
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>825
Arg Leu Ser Gly Thr Ser Arg Ala Ala Ser Thr Thr Pro Thr Tyr
1 5 10 15
<210>826
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>826
Thr Ser Arg Ala Ala Ser Thr Thr Pro Thr Tyr Pro Ala Val Thr
1 5 10 15
<210>827
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>827
Ala Ser Thr Thr Pro Thr Tyr Pro Ala Val Thr Thr Val Tyr Pro
1 5 10 15
<210>828
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>828
Pro Thr Tyr Pro Ala Val Thr Thr Val Tyr Pro Pro Ser Ser Thr
1 5 10 15
<210>829
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>829
Ala Val Thr Thr Val Tyr Pro Pro Ser Ser Thr Ala Lys Ser Ser
1 5 10 15
<210>830
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>830
Val Tyr Pro Pro Ser Ser Thr Ala Lys Ser Ser Val Ser Asn Ala
1 5 10 15
<210>831
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>831
Ser Ser Thr Ala Lys Ser Ser Val Ser Asn Ala Pro Pro Val Ala
1 5 10 15
<210>832
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>832
Lys Ser Ser Val Ser Asn Ala Pro Pro Val Ala Ser Pro Ser Ile
1 5 10 15
<210>833
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>833
Ser Asn Ala Pro Pro Val Ala Ser Pro Ser Ile Leu Lys Pro Gly
1 5 10 15
<210>834
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>834
Pro Val Ala Ser Pro Ser Ile Leu Lys Pro Gly Ala Ser Ala Ala
1 5 10 15
<210>835
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegal ov irus
<400>835
Pro Ser Ile Leu Lys Pro Gly Ala Ser Ala Ala Leu Gln Ser Arg
1 5 10 15
<210>836
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>836
Lys Pro Gly Ala Ser Ala Ala Leu Gln Ser Arg Arg Ser Thr Gly
1 5 10 15
<210>837
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>837
Ser Ala Ala Leu Gln Ser Arg Arg Ser Thr Gly Thr Ala Ala Val
151015
<210>838
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>838
Gln Ser Arg Arg Ser Thr Gly Thr Ala Ala Val Gly Ser Pro Val
1 5 10 15
<210>839
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>839
Ser Thr Gly Thr Ala Ala Val Gly Ser Pro Val Lys Ser Thr Thr
1 5 10 15
<210>840
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>840
Ala Ala Val Gly Ser Pro Val Lys Ser Thr Thr Gly Met Lys Thr
1 5 10 15
<210>841
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>841
Ser Pro Val Lys Ser Thr Thr Gly Met Lys Thr Val Ala Phe Asp
1 5 10 15
<210>842
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>842
Ser Thr Thr Gly Met Lys Thr Val Ala Phe Asp Leu Ser Ser Pro
1 5 10 15
<210>843
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>843
Met Lys Thr Val Ala Phe Asp Leu Ser Ser Pro Gln Lys Ser Gly
1 5 10 15
<210>844
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>844
Ala Phe Asp Leu Ser Ser Pro Gln Lys Ser Gly Thr Gly Pro Gln
1 5 10 15
<210>845
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>845
Ser Ser Pro Gln Lys Ser Gly Thr Gly Pro Gln Pro Gly Ser Ala
1 5 10 15
<210>846
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>846
Lys Ser Gly Thr Gly Pro Gln Pro Gly Ser Ala Gly Met Gly Gly
1 5 10 15
<210>847
<211>15
<212>PRT
<213>Artific ial
<220>
<223>Human cytomegalovirus
<400>847
Gly Pro Gln Pro Gly Ser Ala Gly Met Gly Gly Ala Lys Thr Pro
1 5 10 15
<210>848
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>848
Gly Ser Ala Gly Met Gly Gly Ala Lys Thr Pro Ser Asp Ala Val
1 5 10 15
<210>849
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>849
Met Gly Gly Ala Lys Thr Pro Ser Asp Ala Val Gln Asn Ile Leu
1 5 10 15
<210>850
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>850
Lys Thr Pro Ser Asp Ala Val Gln AsnIle Leu Gln Lys Ile Glu
1 5 10 15
<210>851
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>851
Asp Ala Val Gln Asn Ile Leu Gln Lys Ile Glu Lys Ile Lys Asn
1 5 10 15
<210>852
<211>15
<212>PRT
<213>Artificial
<220>
<223>Human cytomegalovirus
<400>852
Gln Asn Ile Leu Gln Lys Ile Glu Lys Ile Lys Asn Thr Glu Glu
1 5 10 15
<210>853
<211>449
<212>PRT
<213>Homo sapiens
<220>
<221>WT-1
<222>(1)..(449)
<400>853
Met Gly Ser Asp Val Arg Asp Leu Asn Ala Leu Leu Pro Ala Val Pro
1 5 10 15
Ser Leu Gly Gly Gly Gly Gly Cys Ala Leu Pro Val Ser Gly Ala Ala
20 25 30
Gln Trp Ala Pro Val Leu Asp Phe Ala Pro Pro Gly Ala Ser Ala Tyr
35 40 45
Gly Ser Leu Gly Gly Pro Ala Pro Pro Pro Ala Pro Pro Pro Pro Pro
50 55 60
Pro Pro Pro Pro His Ser Phe Ile Lys Gln Glu Pro Ser Trp Gly Gly
65 70 75 80
Ala Glu Pro His Glu Glu Gln Cys Leu Ser Ala Phe Thr Val His Phe
85 90 95
Ser Gly Gln Phe Thr Gly Thr Ala Gly Ala Cys Arg Tyr Gly Pro Phe
100 105 110
Gly Pro Pro Pro Pro Ser Gln Ala Ser Ser Gly Gln Ala Arg Met Phe
115 120 125
Pro Asn Ala Pro Tyr Leu Pro Ser Cys Leu Glu Ser Gln Pro Ala Ile
130 135 140
Arg Asn Gln Gly Tyr Ser Thr Val Thr Phe Asp Gly Thr Pro Ser Tyr
145 150 155 160
Gly His Thr Pro Ser His His Ala Ala Gln Phe Pro Asn His Ser Phe
165 170 175
Lys His Glu Asp Pro Met Gly Gln Gln Gly Ser Leu Gly Glu Gln Gln
180 185 190
Tyr Ser Val Pro Pro Pro Val Tyr Gly Cys His Thr Pro Thr Asp Ser
195 200 205
Cys Thr Gly Ser Gln Ala Leu Leu Leu Arg Thr Pro Tyr Ser Ser Asp
210 215 220
Asn Leu Tyr Gln Met Thr Ser Gln Leu Glu Cys Met Thr Trp Asn Gln
225 230 235 240
Met Asn Leu Gly Ala Thr Leu Lys Gly Val Ala Ala Gly Ser Ser Ser
245 250 255
Ser Val Lys Trp Thr Glu Gly Gln Ser Asn His Ser Thr Gly Tyr Glu
260 265 270
Ser Asp Asn His Thr Thr Pro Ile Leu Cys Gly Ala Gln Tyr Arg Ile
275 280 285
His Thr His Gly Val Phe Arg Gly Ile Gln Asp Val Arg Arg Val Pro
290 295 300
Gly Val Ala Pro Thr Leu Val Arg Ser Ala Ser Glu Thr Ser Glu Lys
305 310 315 320
Arg Pro Phe Met Cys Ala Tyr Pro Gly Cys Asn Lys Arg Tyr Phe Lys
325 330 335
Leu Ser His Leu Gln Met His Ser Arg Lys His Thr Gly Glu Lys Pro
340 345 350
Tyr Gln Cys Asp Phe Lys Asp Cys Glu Arg Arg Phe Ser Arg Ser Asp
355 360 365
Gln Leu Lys Arg His Gln Arg Arg His Thr Gly Val Lys Pro Phe Gln
370 375 380
Cys Lys Thr Cys Gln Arg Lys Phe Ser Arg Ser Asp His Leu Lys Thr
385 390 395 400
His Thr Arg Thr His Thr Gly Lys Thr Ser Glu Lys Pro Phe Ser Cys
405 410 415
Arg Trp Pro Ser Cys Gln Lys Lys Phe Ala Arg Ser Asp Glu Leu Val
420 425 430
Arg His His Asn Met His Gln Arg Asn Met Thr Lys Leu Gln Leu Ala
435 440 445
Leu
<210>854
<211>191
<212>PRT
<213>Hepatitis C virus
<220>
<221>HCV core protein
<222>(1)..(191)
<400>854
Met Ser Thr Asn Pro Lys Pro Gln Arg Lys Thr Lys Arg Asn Thr Asn
1 5 10 15
Arg Arg Pro Gln Asp Val Lys Phe Pro Gly Gly Gly Gln Ile Val Gly
20 25 30
Gly Val Tyr Leu Leu Pro Arg Arg Gly Pro Arg Leu Gly Val Arg Ala
35 40 45
Thr Arg Lys Thr Ser Glu Arg Ser Gln Pro Arg Gly Arg Arg Gln Pro
50 55 60
Ile Pro Lys Ala Arg Arg Pro Glu Gly Arg Ala Trp Ala Gln Pro Gly
65 70 75 80
Tyr Pro Trp Pro Leu Tyr Gly Asn Glu Gly Met Gly Trp Ala Gly Trp
85 90 95
Leu Leu Ser Pro Arg Gly Ser Arg Pro Ser Trp Gly Pro Thr Asp Pro
100 105 110
Arg Arg Arg Ser Arg Asn Leu Gly Lys Val Ile Asp Thr Leu Thr Cys
115 120 125
Gly Phe Ala Asp Leu Met Gly Tyr Ile Pro Leu Val Gly Ala Pro Leu
130 135 140
Gly Gly Ala Ala Arg Ala Leu Ala His Gly Val Arg Val Leu Glu Asp
145 150 155 160
Gly Val Asn Tyr Ala Thr Gly Asn Leu Pro Gly Cys Ser Phe Ser Ile
165 170 175
Phe Leu Leu Ala Leu Leu Ser Cys Leu Thr Ile Pro Ala Ser Ala
180 185 190